Advisor(s)
Abstract(s)
Scientific research has been focused on finding natural occurring molecules from plant origin. Herein, infusion,
decoction and hydroethanolic extracts of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne. from Algeria
were phytochemically characterized by LC-DAD-ESI-MSn, and evaluated regarding bioactive properties (antioxidant
and antibacterial). Flavonol and flavone glycoside derivatives and phenolic acids, specially rosmarinic
acid and kaempferol-O-glucuronide were the major compounds in T. algeriensis extracts. Otherwise, E. alata
presented isoflavones and flavonol derivatives as main compounds, being hydroxypuerarin isomer 1 the major
molecule. Aqueous extracts had significantly higher antioxidant activity, being this activity correlated with the
amount of phenolic compounds. Antimicrobial activity of the extracts was tested against multi-resistant bacteria
strains from clinical isolates. The obtained MIC values indicate that the hydroethanolic extracts revealed the
highest effect, especially the one of T. algeriensis against Gram-positive bacteria. Hence, these plant extracts
could be used in the development of bioactive ingredients.
Description
Keywords
Ephedra alata Infusion/decoction/hydroethanolic extract Phenolic profile/bioactivities Thymus algeriensis
Pedagogical Context
Citation
Ziani, Borhane E.C.; Heleno, Sandrina A.; Bachari, Khaldoun; Dias, Maria Inês; Alves, Maria José; Barros, Lillian; Ferreira, Isabel C.F.R. (2019). Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne. Food Research International. ISSN 0963-9969. 116, p. 312-319