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Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne

2019Journal article Open access
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dc.contributor.authorZiani, Borhane E.C.
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorBachari, Khaldoun
dc.contributor.authorDias, Maria Inês
dc.contributor.authorAlves, Maria José
dc.contributor.authorBarros, Lillian
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2019-01-28T11:52:31Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2019-01-28T11:52:31Z
dc.date.issued2019
dc.description.abstractScientific research has been focused on finding natural occurring molecules from plant origin. Herein, infusion, decoction and hydroethanolic extracts of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne. from Algeria were phytochemically characterized by LC-DAD-ESI-MSn, and evaluated regarding bioactive properties (antioxidant and antibacterial). Flavonol and flavone glycoside derivatives and phenolic acids, specially rosmarinic acid and kaempferol-O-glucuronide were the major compounds in T. algeriensis extracts. Otherwise, E. alata presented isoflavones and flavonol derivatives as main compounds, being hydroxypuerarin isomer 1 the major molecule. Aqueous extracts had significantly higher antioxidant activity, being this activity correlated with the amount of phenolic compounds. Antimicrobial activity of the extracts was tested against multi-resistant bacteria strains from clinical isolates. The obtained MIC values indicate that the hydroethanolic extracts revealed the highest effect, especially the one of T. algeriensis against Gram-positive bacteria. Hence, these plant extracts could be used in the development of bioactive ingredients.
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013), S. Heleno grant (SFRH/BPD/101413/2014) and L. Barros contract. The authors are also grateful to the Interreg España-Portugal for financial support through the project 0377_Iberphenol_6_E.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationZiani, Borhane E.C.; Heleno, Sandrina A.; Bachari, Khaldoun; Dias, Maria Inês; Alves, Maria José; Barros, Lillian; Ferreira, Isabel C.F.R. (2019). Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne. Food Research International. ISSN 0963-9969. 116, p. 312-319en_EN
dc.identifier.doi10.1016/j.foodres.2018.08.041en_EN
dc.identifier.issn0963-9969
dc.identifier.urihttp://hdl.handle.net/10198/18569
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
dc.subjectEphedra alataen_EN
dc.subjectInfusion/decoction/hydroethanolic extracten_EN
dc.subjectPhenolic profile/bioactivitiesen_EN
dc.subjectThymus algeriensisen_EN
dc.titlePhenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decneen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F101413%2F2014/PT
oaire.fundingStream5876
person.familyNameHeleno
person.familyNameDias
person.familyNameAlves
person.familyNameBarros
person.familyNameFerreira
person.givenNameSandrina A.
person.givenNameMaria Inês
person.givenNameMaria José
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-id8B18-3095-6FC9
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person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0001-8744-7814
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridL-5951-2014
person.identifier.ridM-8242-2013
person.identifier.ridM-6624-2016
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id54388787000
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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