Advisor(s)
Abstract(s)
The inflorescences of Calluna vulgaris were nutritionally and chemically characterized. Furthermore,
different organic and aqueous extracts were prepared for the evaluation of their bioactive properties.
From the obtained results, carbohydrates were the major compounds, followed by protein, lipid and
ashes. It was possible to identify the sugars fructose and glucose, five organic acids, 26 individual fatty
acids and the four tocopherol isoforms. Concerning the extract composition, 12 phenolic compounds
were identified, with myricetin-3-O-glucoside and myricetin-O-rhamnoside predominating. Concerning
the bioactive effects, the more polar extracts showed not only the highest amount in phenolic compounds,
but also the strongest antioxidant and antibacterial activities. In contrast, for the anti-inflammatory
and cytotoxic potential, the most effective extracts were the n-hexane and the ethyl acetate extracts,
respectively. C. vulgaris presented a wide range of biological effects, highlighting their capacity to inhibit
pathogenic bacteria without affecting beneficial microflora, corroborating their use in traditional medicine.
Description
Keywords
Pedagogical Context
Citation
Mandim, Filipa; Barros, Lillian; Calhelha, Ricardo C.; Abreu, Rui M.V.; Pinela, José; Alves, Maria José; Heleno, Sandrina; Santos, P. F.; Ferreira, Isabel C.F.R. (2019). Calluna vulgaris (L.) Hull: Chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota. Food and Function. ISSN 2042-6496. 10, p. 78-89