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Phenolic extract from the fruiting body and spores of a medicinal mushroom - Ganoderma lucidum: investigating their antioxidant potential and antitumor cell growth inhibitory effects

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Mushrooms are a source of bioactive compounds, some of them with antioxidant properties or with antitumour potential (1). Ganoderma lucidum is one of the most extensively studied mushrooms due to its medicinal properties, as functional food and as chemopreventive (2). Some of the pharmacological properties of its compounds (e.g. polysaccharides, glucoproteins, triterpenes and steroids) have been related to antitumor activity, including cell cycle arrest and induction of apoptosis (3). Nevertheless, the bioactive properties of its phenolic compounds remain unevaluated.

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Heleno, Sandrina A.; Tavares, Catarina; Vaz, Josiana A.; Almeida, Gabriela M.; Martins, Anabela; Queiroz, Maria João R.P.; Vasconcelos, M. Helena; Ferreira, Isabel C.F.R. (2012). Phenolic extract from the fruiting body and spores of a medicinal mushroom - Ganoderma lucidum: investigating their antioxidant potential and antitumor cell growth inhibitory effects. In 3rd I3S Scientific Retreat IBMC/INEB/IPATIMUP. Póvoa de Varzim

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