Sleep quality and hormonal levels of ghrelin and leptin in the elderly: a cross-sectional study

Alves, Sara; Capristano, Jeovana; Sá,  Leandro Moreira de; Mendes, Eugénia; Fernandes, Hélder; Vaz, Josiana A.

http://hdl.handle.net/10198/34508

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Authors

Alves, Sara

Capristano, Jeovana

Sá, Leandro Moreira de

Mendes, Eugénia

Fernandes, Hélder

Vaz, Josiana A.

Abstract(s)

The increase in life expectancy prompts a critical examination of the quality of aging in contemporary societies. Ageing causes alterations in the circadian sleep-wake cycle, which are closely linked to cellular senescence. Research indicates that insufficient sleep can accelerate inflammation and oxidative stress, highlighting the importance of good sleep hygiene for overall health and reducing the effects of ageing. Sleep quality is closely connected to hormonal balance, particularly ghrelin, leptin, melatonin, and serotonin. These hormones play significant roles in regulating appetite, metabolism, sleep patterns, and emotional well-being. This study aimed to evaluate sleep quality in a group of elderly individuals (N=25) and its relationship with serum levels of ghrelin and leptin. Sleep quality was assessed using the Portuguese version of the Pittsburgh Sleep Quality Index. Blood collection for laboratory tests was performed according to WHO guidelines

Keywords

Sleep quality Aged

URI

http://hdl.handle.net/10198/34508

Citation

Alves, Sara; Capristano, Jeovana; Sá, Leandro Moreira de; Mendes, Eugénia; Fernandes, Hélder; Vaz, Josiana A. (2025). Sleep quality and hormonal levels of ghrelin and leptin in the elderly: a cross-sectional study. In III Congresso BioMedLab da Associação Portuguesa de Ciências Biomédicas Laboratoriais. Lisboa