Urinary levels of monohydroxyl PAH metabolites in portuguese firefighters: background levels and impact of tobacco smoke

Oliveira, Marta; Slezakova, Klara; Gomes, Maria José; Azevedo, Ana; Teixeira, João Paulo Fernandes; Delerue-Matos, Cristina; Pereira, Maria do Carmo; Morais, Simone

http://hdl.handle.net/10198/13606

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Authors

Oliveira, Marta

Slezakova, Klara

Gomes, Maria José

Azevedo, Ana

Teixeira, João Paulo Fernandes

Delerue-Matos, Cristina

Pereira, Maria do Carmo

Morais, Simone

Abstract(s)

Firefighting occupational exposure is classified as possible carcinogen to humans by the International Agency for Research on Cancer and the US National Institute for Occupational Safety and Health [1,2].  Tobacco smoke is a very important factor in the assessment of occupational exposure of workers, since the prolonged exposure to tobacco smoke is by itself the major cause of lung cancer [3]. The consumption of tobacco is responsible for the exposure to many smoke components including more than sixty known carcinogens, including some polycyclic aromatic hydrocarbons (PAHs) [4].  PAHs are ubiquitous compounds formed during pyrolysis or incomplete combustion of organic matter, being well-known for their toxic, mutagenic, and carcinogenic properties to humans [5,6]. So far, the impact of tobacco smoke on firefighters’ total exposure to PAHs is very limited.

Keywords

Monohydroxyl PAH Urinary levels Firefighters Tobacco smoke

URI

http://hdl.handle.net/10198/13606

Citation

Oliveira, M.; Slezakova, K.; Gomes, Maria José; Azevedo, Ana; Teixeira, J.P.; Delerue-Matos, C.; Pereira, M.C.; Morais, S. (2016). Urinary levels of monohydroxyl PAH metabolites in Portuguese firefighters: background levels and impact of tobacco smoke. In XXII Encontro Luso-Galego de Química. Bragança