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Studies indicate that infections caused by pathogenic microorganisms may result in chronic
diseases, such as obstructive pulmonary disease, chronic rhinosinusitis, aspergillosis etc. In
addition, microorganisms of clinical relevance have developed multiple drug resistance which
has seriously increased recently, threatening to global public health. Therefore, alternative
strategies for treatment, which include natural sourced substances of traditional use, are
required. Mushrooms have been recognized for their nutritional properties and richness in
bioactive compounds. As the third most cultivated mushroom in the world, P. ostreatus has
been chemically characterized on several occasions to prospect bioactive molecules. Herein,
we report detailed chemical profile regarding nutrients, as well as the ability of the methanolic
extract obtained from commercially cultivated fruiting bodies to reduce in vitro growth of
selected pathogenic microorganisms, some of which are causatives of chronic diseases.
Carbohydrates were the most abundant compounds (80 g/100 g dw), followed by proteins (10
g/100 g dw) and fat (2 g/100 g dw). Trehalose was the most abundant sugar (17 g/100 g dw),
whereas mannitol was present in lower amounts (0.9 g/100 g dw). As for the fatty acids,
polyunsaturated fatty acids were predominant in the sample (56%), followed by saturated
fatty acids (25%) and monounsaturated fatty acids (19%). With energy value of 382 kcal/100
g dw, cultivated P. ostreatus represents a healthy, low-caloric food, recommended for use on
a daily basis. The antimicrobial potential of the extract was evaluated against pathogenic
Gram negative bacteria P. aeruginosa, which was strongly inhibited (MIC value = 0.51
mg/mL, MBC value = 1.02 mg/mL). Regarding antifungal activity, the extract exhibited very
good inhibitory activity against a range of Aspergillus species, which are considered
responsible for aspergillosis. Hence, data suggest that cultivated mushroom P. ostreatus is a
good source of nutritional components beneficial to human health. Furthermore, its extract
represents a potent bioactive agent against pathogenic microorganisms, which are potential
causal agents of chronic diseases.
Descrição
Palavras-chave
Pleurotus ostreatus Aspergillosis Pseudomonas aeruginosa Nutritional value
Contexto Educativo
Citação
Petrović, Jovana; Ćirić, Ana; Heleno, Sandrina A.; Barros, Lillian; Ferreira, Isabel C.F.R.; Glamočlija, Jasmina; Soković, Marina (2016). Pleurotus Ostreatus (JACQ. EX.FR.) P.K.: a highly nutritious edible mushroom cultivated in Serbia as a potential remedy for chronic infectious diseases. In 13th congress of Nutrition. p. 273-274. Belgrade, Servia