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Free radical formation is associated with the normal natural metabolism of aerobic cells. The oxygen consumption inherent to cell growth leads to the generation of a series of oxygen free radicals. The interaction of these species with lipid molecules produces new radicals that may interact with biological systems in a cytotoxic manner. Free radicals and their uncontrolled production are responsible for several pathological processes, such as certain tumours (prostate and colon cancers) the reducing properties of diarylamines make them very important as antioxidants, especially as radical scavengers.
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Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.; Barros, Lillian; Abreu, Ana S.; Ferreira, Paula M.T. (2007). Antioxidant properties of diarylamines derivatives of benzo[b]thiophenes and amino acids. In First Iberic Meeting on Medicinal Chemistry- Anticancer Agents. Régua