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Advisor(s)
Abstract(s)
Geranium robertianum L. has been used in folk medicine and herbalism practice for the treatment of
various conditions, but the study of its bioactivity has been barely addressed. Although its phytochemical
composition has received some attention, contributions to the nutritional composition are practically
unknown. Herein, G. robertianum gathered in Trás-os-Montes, Northeastern Portugal, was chemically
characterized regarding nutritional parameters, and the antioxidant activity and cytotoxicity against
several human tumor cell lines and non-tumor porcine liver primary cells of several aqueous and organic
extracts were evaluated. G. robertianum showed to be an equilibrated valuable herb, rich in carbohydrates
and proteins, and poor in fat, providing sugars, tocopherols, organic and essential fatty acids. Amongst the
extracts, the acetone one showed the highest total phenol and total flavonoid contents, as well as the
greatest antioxidant and cytotoxic activities. This extract showed to contain hydrolysable tannins (e.g. geraniin
and castalagin/vescalagin), as the main phenolic compounds
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Keywords
Citation
Graça, Vânia C.; Barros, Lillian; Calhelha, Ricardo C.; Dias, Maria Inês; Carvalho, Ana Maria; Santos-Buelga, Celestino; Santos, P.F.; Ferreira, Isabel C.F.R. (2016) - Chemical characterization and bioactive properties of aqueous and organic extracts of Geranium robertianum L. (2016). Food & Function. ISSN 2042-6496. 7:9, p. 3807-3814
Publisher
Food & Function