Advisor(s)
Abstract(s)
Carotenoid-rich fractions (CRF) from pulp and peel of a new variety of purple tomato were investigated in
comparison to a Red Cherry variety regarding carotenoids characterization, antioxidant capacity, and inhibition
of proliferation of four tumor cell lines. CRF from peel of Purple tomato contains lutein, lycopene, and β-carotene
up to 6, 1.5, and 2.5 times more than that of Red Cherry and it exhibited the highest antioxidant activity at 400
μg/mL, reaching 82% and 97% in DPPH and ABTS þ assays, respectively. Besides that, the Purple peel showed the
highest scavenging lipoperoxides capacity as well as displayed the highest ferric reducing antioxidant power
compared to the other CRF. In turn, the Red Cherry pulp CRF showed the highest antiproliferative activity against
four tumor cell lines (MCF-7, NCI-H460, HeLa, and HepG2) at non-toxic concentrations. High concentration of
neurosporene, and lycopene in Red Cherry pulp CRF show to be related to the good antiproliferative activity
found on it. Therefore, this new variety of nutrient-rich purple tomato could be explored as well as the commercial
variety Red Cherry, since both are good sources of dietary carotenoids with health-promoting properties.
Description
Keywords
Antioxidant Antiproliferative activity Carotene Chemical characterization of food Chemical composition of food Food biochemistry Food component analysis Food science Hepatotoxicity Lycopene Phenolic compound Solanum lycopersicum L.
Pedagogical Context
Citation
Campestrini, Luciano H.; Melo, Priscilla S.; Peres, Lázaro E.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Alencar, Severino M. (2019). A new variety of purple tomato as a rich source of bioactive carotenoids and its potential health benefits. Heliyon. ISSN 2405-8440. 5, p. 1-8