Publication
A new variety of purple tomato as a rich source of bioactive carotenoids and its potential health benefits
| dc.contributor.author | Campestrini, Luciano H. | |
| dc.contributor.author | Melo, Priscilla S. | |
| dc.contributor.author | Peres, Lázaro E.P. | |
| dc.contributor.author | Calhelha, Ricardo C. | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.contributor.author | Alencar, Severino M. | |
| dc.date.accessioned | 2018-02-19T10:00:00Z | |
| dc.date.accessioned | 2020-01-06T14:09:26Z | |
| dc.date.available | 2018-01-19T10:00:00Z | |
| dc.date.available | 2020-01-06T14:09:26Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Carotenoid-rich fractions (CRF) from pulp and peel of a new variety of purple tomato were investigated in comparison to a Red Cherry variety regarding carotenoids characterization, antioxidant capacity, and inhibition of proliferation of four tumor cell lines. CRF from peel of Purple tomato contains lutein, lycopene, and β-carotene up to 6, 1.5, and 2.5 times more than that of Red Cherry and it exhibited the highest antioxidant activity at 400 μg/mL, reaching 82% and 97% in DPPH and ABTS þ assays, respectively. Besides that, the Purple peel showed the highest scavenging lipoperoxides capacity as well as displayed the highest ferric reducing antioxidant power compared to the other CRF. In turn, the Red Cherry pulp CRF showed the highest antiproliferative activity against four tumor cell lines (MCF-7, NCI-H460, HeLa, and HepG2) at non-toxic concentrations. High concentration of neurosporene, and lycopene in Red Cherry pulp CRF show to be related to the good antiproliferative activity found on it. Therefore, this new variety of nutrient-rich purple tomato could be explored as well as the commercial variety Red Cherry, since both are good sources of dietary carotenoids with health-promoting properties. | |
| dc.description.sponsorship | This work was supported by Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) [grant number 2014/11150-6]; and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) [grant numbers 306722/2012-7, 307040/2014-3, and 150015/2018-6) from Brazil; and Fundação para a Ciência e a Tecnologia (FCT) for CIMO [grant numbers Pest OE/AGR/UI0690/2014; SFRH/BPD/68344/2010] from Portugal. | |
| dc.description.version | info:eu-repo/semantics/publishedVersion | en_EN |
| dc.identifier.citation | Campestrini, Luciano H.; Melo, Priscilla S.; Peres, Lázaro E.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Alencar, Severino M. (2019). A new variety of purple tomato as a rich source of bioactive carotenoids and its potential health benefits. Heliyon. ISSN 2405-8440. 5, p. 1-8 | en_EN |
| dc.identifier.doi | 10.1016/j.heliyon.2019.e02831 | en_EN |
| dc.identifier.issn | 2405-8440 | |
| dc.identifier.uri | http://hdl.handle.net/10198/20232 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | en_EN |
| dc.subject | Antioxidant | en_EN |
| dc.subject | Antiproliferative activity | en_EN |
| dc.subject | Carotene | en_EN |
| dc.subject | Chemical characterization of food | en_EN |
| dc.subject | Chemical composition of food | en_EN |
| dc.subject | Food biochemistry | en_EN |
| dc.subject | Food component analysis | en_EN |
| dc.subject | Food science | en_EN |
| dc.subject | Hepatotoxicity | en_EN |
| dc.subject | Lycopene | en_EN |
| dc.subject | Phenolic compound | en_EN |
| dc.subject | Solanum lycopersicum L. | en_EN |
| dc.title | A new variety of purple tomato as a rich source of bioactive carotenoids and its potential health benefits | en_EN |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/PEst-OE%2FAGR%2FUI0690%2F2014/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F68344%2F2010/PT | |
| oaire.fundingStream | 5876 | |
| oaire.fundingStream | SFRH | |
| person.familyName | Calhelha | |
| person.familyName | Ferreira | |
| person.givenName | Ricardo C. | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | F313-E3CE-554E | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0002-6801-4578 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | J-2172-2014 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 6507978333 | |
| person.identifier.scopus-author-id | 36868826600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | en_EN |
| rcaap.type | article | en_EN |
| relation.isAuthorOfPublication | 2d5d1a41-7561-4a01-871c-b4c97da35053 | |
| relation.isAuthorOfPublication | bd0d1537-2e03-41fb-b27a-140af9c35db8 | |
| relation.isAuthorOfPublication.latestForDiscovery | 2d5d1a41-7561-4a01-871c-b4c97da35053 | |
| relation.isProjectOfPublication | f3fc3f7e-17b1-488f-abea-2601a44654b1 | |
| relation.isProjectOfPublication | 11192b59-0b2d-42b9-bf36-31bc50f8bccc | |
| relation.isProjectOfPublication.latestForDiscovery | f3fc3f7e-17b1-488f-abea-2601a44654b1 |