CIMO - Resumos Indexados à WoS/Scopus
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- Free radical scavenging activity of different almond (Prunus dulcis) varietiesPublication . Barreira, João C.M.; Ferreira, Isabel C.F.R.; Oliveira, Beatriz; Pereira, J.A.Reactive oxygen species are known to be implicated in many cell disorders and in the development of many diseases including cardiovascular diseases atherosclerosis, cataracts, chronic inflammation or neurodegenerative diseases such as Alzheimer’s or Parkinson 's disease. Thus, synthetic antioxidants are widely used in the food industry, bur, because of their toxic and carcinogenic effects, their use is being restricted.
- Body composition and body image perception in portuguese and spanish college students: comparative study between overweight /obese and normal weight womenPublication . Pereira, Elza; Lacerda, Fernanda; Valador, Natacha; Ferro-Lebres, Vera; Arroyo-Izaga, MartaObjective: To evaluate body image perception and compare with real measures of body composition between overweight/obese and normal weight women college students. Subjects: The reported sample included 600 students from Portugal and Spain. Material and Methods: The anthropometry variables: weight, height, skinfolds, circumferences and body mass index, waist-hip ratio, percentage of body fat and fat-free mass- FFM were compared with reference values. The body image perception and satisfaction were estimated using Somatomorphic Matrix and Body Shape Questionnaire (BSQ34). With the difference between actual and ideal measures was obtained the dissatisfaction through body image. For data analysis was used t-test and Pearson correlation. Results:10,7% of the Spanish sample was overweight/obese. Statistical significance was found between real and ideal FFM (P<0,01), showing a medium body dissatisfaction. Fat mass was well estimated. The Portuguese measures are elapsing now. The results will be finished before the congress date. Conclusions: These results constitute a first approach of body image perception and satisfaction, in Portuguese and Spanish students. Recent studies consider the cultural thinness preoccupation, the weight prejudice and disturbances in body image, mainly a discrepancy between perceived and ideal body image, extending beyond the health risks associated with obesity, and have become a serious problem. And the effect of body size and composition feedback is more pronounced in overweighted. Our study shows the importance of public health actions in the education of body image perception and satisfaction in Portugal and Spain, as a measure preventing eating disorders and other mental disturbances, especially between overweight/obese women.
- Maternal overweight and obesity versus breastfeeding successPublication . Lucas, Cláudia; Teixeira, Diana; Silvestre, Vera; Almeida-de-Souza, Juliana; Ferreira, Eva Pinto
- Progestagen treatment associated with different doses of eCG to advance the breeding season in Churra Galega Bragançana ewesPublication . Valentim, Ramiro; Azevedo, Jorge; Mendonça, Álvaro; Fontes, Paulo; Galvão, Lurdes; Cardoso, Manuel; Velasco, Helena; Maurício, Raimundo; Correia, Teresa MontenegroIn order to assess the effects of a long-term progestagen treatment associated with different doses of eCG (equine Chorionic Gonadotropin) to advance the breeding season in Portuguese Churra Galega Bragançana ewes, an initial group of 41 females (2 were later rejected) aged between 2 and 7 years was used. In middle May, all ewes were treated with an intravaginal sponge impregnated with 20 mg of fluorogestone acetate (FGA) for 12 days. Half ewes received an injection (i.m.) of 500 UI of eCG and the other half an injection (i.m.) of 750 UI of eCG at sponge removal time. Blood samples were taken for progesterone determination and 4 intact rams with harness marker were used to identify the estrus. A transrectal ultrasound scanning was performed for pregnancy diagnosis. In early May, 63.4% of all ewes were in seasonal anoestrous. Treatments resulted in 97.4% ewes in estrus and 89.7% ewes with corpora lutea (CL) (Chi2 = 60.595; P<0.001). The higher dose of eCG had a positive effect in estrus (94.4% vs. 100.0%; Chi2 = 6.186; P<0.05) and pregnancy (61.1% vs. 81.0%; Chi2 = 9.713; P<0.01) and fertility (61.1% vs. 76.2%; Chi2 = 5.214; P<0.05) rates. The eCG dose had no effect in ewes with CL (88.9% vs. 90.5%; Chi2 = 0.053; P>0.05) and prolificacy (1.5 ± 0.8 vs. 1.7 ± 0.6; P>0.05). In conclusion, a long-term FGA treatment may be used to advance the breeding season in Churra Galega Bragançana ewes and the reproductive response depends on the eCG dose.
- Depressive symptoms and alcohol use among adolescentsPublication . Pinto, Isabel C.; Fraga, Sílvia; Ramos, ElisabeteAlcohol is the most consumed substance by young people, sometimes it’s associated with depressive symptoms. Objective: Assess the factors associated with alcohol use among 13-year-old teenagers, like depressive symptoms. Methods: Data of a population-based cohort of urban teenagers included cross-sectional information of 919 boys and 1016 girls collected by self-reported questionnaire. Depressive symptoms were evaluated using Beck Depressive Inventory II (BDI). The Mann-Whitney test was used to compare medians. Odds ratio (OR) and multiple linear regression (β) were performed to estimate the magnitude of associations with 95% confidence intervals (95%CI). The final model was adjusted for parents’ education, sports, smoking, have friends who drink and parents’ history of depression. Results: Overall 515(50.0%) girls and 425(44.9%) boys have experimented alcoholic beverages and, 48(4.7%) girls and 62(6.6%) boys have drunk(one drink at least once time per month) at 13-year-old. For both genders, after adjustment, being experimenter was significantly associated with parents’ education, tobacco use and friends who drink. In girls, characteristics that was significantly associated to be drinker were tobacco use OR=6.9(3.1-15.2) and friends who drink OR=6.4(2.7-15.2). In boys, to be drinker was associated with tobacco use OR=5.9(2.7-13.0), friends who drink OR=7.3(3.5-15.4) and cohabiting with people who drink OR=5.1(1.4-17.6). Adolescents who have drunk presented a high score in BDI [median(25p-75p)] in girls[6.01(2.00-10.00)vs.6.38(3.00-11.99),p=0.002)] and in boys[3.00(1.01-6.01)vs.3.99(1.01-6.99),p=0.039]. After adjustment, the association was not significant in girls(β=0.583,95%CI[-0.483;1.648]) in boys(β=0.623,95%CI[-0.170;1.417]). Conclusions: Among 13-year-old adolescents parents’ education, smoking and friends who drink were associated with drinking behaviour. After adjustment, depressive symptoms did not show a significant association with alcohol use.
- Unusual flavones in cytisus desf.Publication . Pereira, Olívia R.; Domingues, Maria R.M.; Silva, Adrián; Cardoso, Susana M.Cytisus Desf. (Fabaceae) is a diversified genus enclosing approximately sixty species, which are particularly found around the Mediterranean Sea. Many plants of this genus exhibit bioactive properties such as diuretic, hypnotic, anxiolytic, antiparasitic, antidiabetic and antioxidant [1] and, in particular the latter, has been closely associated to the high content in flavonoids [2]. The present work aims to contribute to the knowledge of Cytisus Desf. chemical composition, through the identification of new flavonoids in that genus. The compounds in focus were detected in ethanolic extracts of Cytisus multiflorus flowers by means of HPLC-DAD, ESI-MS and MSn analyses. These included the two isomers 2′′-O-pentosyl-6-C-hexosyl-luteolin and 2′′-O-pentosyl-8-C-hexosyl-luteolin (MW 580 Da), the two isomers 2′′-O-pentosyl-6-C-hexosyl-apigenin and 2′′-O-pentosyl-8-C-hexosyl-apigenin (MW 564 Da), the 6′′-O-(3-hydroxy-3-methylglutaroyl)-2′′-O-pentosyl-C-hexosyl-luteolin (MW 724 Da) and the 6′′-O-(3-hydroxy-3-methylglutaroyl)-2′′-O-pentosyl-C-hexosyl-apigenin (MW 708 Da). Attending that half of the these compounds were herein described for first time in Fabaceae, overall, the present work is a valuable contribution for the phenolic elucidation of Cytisus genus as well as the Fabaceae family.
- Polymeric biophenols in olive mill wastewatersPublication . Cardoso, Susana M.; Falcão, Soraia; Peres, António M.; Pereira, Olívia R.; Domingues, Maria R.M.
- Cistus ladanifer as a source of phenolic compounds with antifungal activityPublication . Barros, Lillian; Dueñas, Montserrat; Alves, Carlos Tiago; Silva, Sónia; Henriques, Mariana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.A screening of the antifungal potential of phenolic extract of Cistus ladanifer from Northeast Portugal, against Candida species was performed. The extract was characterized by HPLC-DAD-ESI/MS. Phenolic acids and derivatives, ellagic acid derivatives and flavonoids, such as catechins, flavonols and flavones, were found in the sample. The most abundant group was ellagic acid derivatives in which punicalagin gallate, a derivative of punicalagin attached to gallic acid, was found in highest amount. These compounds could be related to the strong inhibition of C. albicans, C. glabrata and C. parapsilosis growth. Moreover, the best antifungal activity was against C. glabrata, where the studied extract was able to cause at least 3 Log of reduction at concentrations below 50 µg/mL and a total growth inhibition at concentrations above 625 µg/mL.
- Influence of socio-demographic issues in body mass index (bmi) of drug addicts in methadone maintenance treatmentPublication . Ferro-Lebres, Vera; Costa, Ana Filipa; Alves, Daniela; Custódio, Daniela; Natário, Liliana; Andrade, FernandoThe purpose of this study was to investigate the infl uence of social factors on the nutritional status of drug addicts. 60 drug addicts in methadone maintenance treatment of Integrated Response Center (CRI)of Bragança were evaluated. Nutritional assessment was performed by measuring the weight and height and then calculated the body mass index. The socio-demographic data were collected through a questionnaire constructed for this purpose. PASW 19.0 for Windows. The average body mass index (BMI) was 22.46 ± 3.36 kg/m2 and based on this parameter 13.3% were underweight, 65% normal weight, 20.0% overweight and 1.7% obesity grade I. BMI was signifi cantly higher in addicts who live with a spouse in relation to other housing contexts (p< 0.005). In terms of marital status, unmarried addicts had a significantly lower BMI compared to other situations. Individuals have an average of 4.10 ± 4.47 years of treatment and 78.3% performed less than 3 meals/day. The socio-demographic conditions must be taken into consideration in the process of intervention with this population. More studies must be performed in other to clarify other food behaviour variables in drug users populations.
- Portuguese propolis enriched phenolic extract: reactive oxygen scavenging and cytoprotective activitiesPublication . Pereira, Olívia R.; Macias, Rócio I.R.; Perez, María J.; Marín, Jose J.G.; Cardoso, Susana M.Propolis, a resinous natural product produced by honeybees, is claimed to have a wide range of beneficial activities for human health which have been attributed to its phenolics. In general, phenolics account for approximately half of propolis weight, although its content and composition can greatly vary with propolis geographical origin. This study aims determining the antioxidant and cytoprotective properties of Northeast Portuguese propolis. The propolis hydroethanolic purified extract (PPE) was obtained by extraction at 70 °C/1 h and recovery onto SPE C18 cartridges. Total phenolic content and identification of the main phenolics in the PPE were assessed by the Folin Ciocalteu method and by HPLC-DAD analysis, respectively. The reactive oxygen species (ROS) scavenging and cytoprotective properties of PPE were evaluated in dichromate potassium-stimulated (DK) HepG2 cells model. ROS scavenging ability was measured by flow cytometry, after DK incubation for 48 h and cytoprotective activity was estimated by the MTT assay, after DK exposure for 6 h or 72 h. The total amount of phenolics in the PPE accounted for 375.4±5.8 mg GAE/g of extract and this was enriched in chrysin, pinocembrin and pinobanksin-3-O-acetate. Bioactivity assays showed that the PPE decreased the rate of ROS production about 50% and exerted an effective protection against the reduction of cell viability of 9% and 22%, for HepG2 cells exposed to DK for 6 h and 72 h, respectively. Overall the results emphasize important activities of PPE that can be related to the high content of phenolic compounds.