Percorrer por autor "Zielinski, Acacio A.F."
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- Bioactive activities of the phenolic extract from sterile bracts of Araucaria angustifoliaPublication . Fischer, Thais E.; Marcondes, Amanda; Zardo, Danianni M.; Nogueira, Alessandro; Calhelha, Ricardo C.; Vaz, Josiana A.; Barros, Lillian; Zielinski, Acacio A.F.; Alberti, Aline
- Green extraction of anthocyanin from red cabbage waste using acid whey as a promising bio-based solventPublication . Oliveira, Jaine; Benvenutti, Laís; Albuquerque, Bianca R.; Finimundy, Tiane C.; Mandim, Filipa; Pires, Tânia C.S.P.; Pereira, Carla; Corrêa, Rúbia C.G.; Barros, Lillian; Zielinski, Acacio A.F.The use of acid whey as a biological-based solvent may be an innovative and sustainable strategy to add value to agro-industrial by-products. This study assessed acid whey as a solvent for extracting anthocyanins from discarded red cabbage leaves. Methods such as Heating and Stirring Extraction (HSE), Ultrasound-Assisted Extraction (UAE), and Pressurized Liquid Extraction (PLE) were compared using acid whey or acidified ethanol as solvents. The yield of anthocyanin extract from acid whey is approximately 7 % lower compared to that obtained from acidified ethanol. All extracts exhibited in vitro antioxidant activity. Anthocyanin-rich extracts from red cabbage leaves revealed the predominant presence of cyanidin-3-O-(feruloyl)-sophoroside-5-O-glucoside (949 m/z). No cytotoxic effects were observed in the tested extracts, underscoring their safety and potential for industrial applications. Furthermore, incorporating powdered extracts into marshmallows yielded promising results as a natural colorant, emphasizing their versatility. These findings underscore acid whey role as a sustainable biobased solvent for extracting anthocyanins from red cabbage waste. Industrial relevance: The use of acid whey as a solvent for extracting anthocyanins from purple cabbage leaves is a valuable alternative in the agroindustry. This practice adds value to by-products and promotes sustainability. Emerging technologies, such as ultrasound-assisted extraction (UAE) and pressurized liquid extraction (PLE), enhance the efficiency of this process. Analysis shows that acid whey is efficient and environmentally friendly, yielding extracts with antioxidant properties. These extracts can also serve as natural colorants, meeting the demand for natural ingredients. Thus, acid whey enhances sustainability in agroindustrial production.
- Jatoba (Hymenaea courbaril L.) Pod Residue: A Source of Phenolic Compounds as Valuable BiomoleculesPublication . Del Angelo, Gabriela Lucca; Oliveira, Isabela Silva de; Albuquerque, Bianca R.; Kagueyama, Samanta Shiraishi; Silva, Tamires Barlati Vieira; Santos Filho, José Rivaldo dos; Dias, Maria Inês; Pereira, Carla; Calhelha, Ricardo C.; Alves, Maria José; Ferrari, Ariana; Yamaguchi, Natalia Ueda; Zielinski, Acacio A.F.; Bracht, Adelar; Peralta, Rosane M.; Corrêa, Rúbia C.G.This study aimed at investigating the chemical composition and a selected group of bioactivities of jatoba (Hymenaea courbaril L.) pod residue. An aqueous extract (deionized water; AE) and a hydroethanolic extract (ethanol: deionized water, 70:30 v/v; ETOH) were obtained via maceration. Ten phenolic compounds were characterized via LC-DAD-ESI/MSn: seven procyanidins, two quercetin derivatives and one taxifolin derivative, with dimers and trimers of procyanidins being the main components of both extracts. Total phenolic compound levels of 2.42 ± 0.06 and 11 ± 1 mg/g were found in AE and ETOH, respectively; however, only seven compounds were identified in ETOH. The jatoba pod residue extracts showed notable antioxidant activities: ETOH had greater antioxidant potential in the OxHLIA and DPPH assays (IC50 = 25.4 μg/mL and 0.71 μg/mL, respectively); however, EA demonstrated greater potential in the FRAP system (IC50 = 2001.0 μM TE/mg). Only AE showed antiproliferative potential, being effective against cell lines of gastric (GI50 = 35 ± 1 μg/mL) and breast (GI50 = 89 ± 4 μg/mL) adenocarcinomas. Likewise, only AE showed modest anti-inflammatory potential (IC50 = 225 ± 2 μg/mL) in mouse macrophages. Bacteriostatic effects against bacteria were exerted by both extracts. Enterococcus faecalis and Listeria monocytogenes (MICs = 2.5 mg/mL) were especially sensitive to the ETOH extract. Taken together, the results suggest potential for jatoba pod residue as a source of molecules with biological activities and with possible industrial applications.