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Advisor(s)
Abstract(s)
This study aimed at investigating the chemical composition and a selected group of
bioactivities of jatoba (Hymenaea courbaril L.) pod residue. An aqueous extract (deionized water;
AE) and a hydroethanolic extract (ethanol: deionized water, 70:30 v/v; ETOH) were obtained via
maceration. Ten phenolic compounds were characterized via LC-DAD-ESI/MSn: seven procyanidins,
two quercetin derivatives and one taxifolin derivative, with dimers and trimers of procyanidins
being the main components of both extracts. Total phenolic compound levels of 2.42 ± 0.06 and
11 ± 1 mg/g were found in AE and ETOH, respectively; however, only seven compounds were
identified in ETOH. The jatoba pod residue extracts showed notable antioxidant activities: ETOH had
greater antioxidant potential in the OxHLIA and DPPH assays (IC50 = 25.4 μg/mL and 0.71 μg/mL,
respectively); however, EA demonstrated greater potential in the FRAP system (IC50 = 2001.0 μM
TE/mg). Only AE showed antiproliferative potential, being effective against cell lines of gastric
(GI50 = 35 ± 1 μg/mL) and breast (GI50 = 89 ± 4 μg/mL) adenocarcinomas. Likewise, only AE showed
modest anti-inflammatory potential (IC50 = 225 ± 2 μg/mL) in mouse macrophages. Bacteriostatic
effects against bacteria were exerted by both extracts. Enterococcus faecalis and Listeria monocytogenes
(MICs = 2.5 mg/mL) were especially sensitive to the ETOH extract. Taken together, the results suggest
potential for jatoba pod residue as a source of molecules with biological activities and with possible
industrial applications.
Description
Keywords
Food waste recovery Phenolic compounds Antioxidant potential Antiproliferative potential Antimicrobial activity Upcycling
Pedagogical Context
Citation
Del Angelo, Gabriela Lucca; Oliveira, Isabela Silva de; Albuquerque, Bianca Rodrigues de; Kagueyama, Samanta Shiraishi; Silva, Tamires Barlati Vieira da; Santos Filho, José Rivaldo dos; Dias, Maria Inês; Pereira, Carla; Calhelha, Ricardo C.; Alves, Maria José; Ferrari, Ariana; Yamaguchi, Natalia Ueda; Zielinski, Acácio Antonio Ferreira; Bracht, Adelar; Peralta, Rosane Marina; Corrêa, Rúbia Carvalho Gomes (2024). Jatoba (Hymenaea courbaril L.) Pod Residue: A Source of Phenolic Compounds as Valuable Biomolecules. Plants. ISSN 2223-7747. 13:22, p. 1-12
Publisher
MDPI