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Novel flavones in Lamium L. genus
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Orientador(es)
Resumo(s)
The main aim of this work is to determine the phenolic composition of a Lamium album L. purified extract, in order to contribute for the chemical characterization of this plant. Moreover, it also intends to emphasize its antioxidant properties. As established by HPLC-DAD and ESI-MSn combined analysis, verbascoside was the major phenolic constituent of Lamium album L. purified extract, as previously described by other authors [1]. Still, we could also detect, for the first time in Lamium genus, significant amounts of isobervascoside and of isoscutellarein derivatives. As confirmed by NMR analysis, the major isoscutellarein derivative in Lamium album L. purified extract was the isoscutellarein-7-O-(6-O-acetyl-β-allosyl)(1→2)-β-glucoside, but isoscutellarein-7-O-allosyl(1→2)glucoside and of O-methyl derivatives of these two compounds were also present in considerable amounts. Aditionally, the extract showed good antioxidant activities in in vitro experiments. Overall, the present study contributes for the chemical and biological characterization of L. album L.
Descrição
Palavras-chave
Lamium L. Isoscutellarein derivatives HPLC-DAD ESI-MSn RMN
Contexto Educativo
Citação
Pereira, Olívia R.; Domingues, Maria R. M.; Silva, Artur M. S.; Cardoso, Susana M. (2012). Novel flavones in Lamium L. genus. In 11º Encontro Química dos Alimentos. ISBN 978-972-745-141-8
Editora
Instituto Politécnico de Bragança