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Blood flow in microchannels manufactured by a low cost technique: xurography

2013Book part Open access
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dc.contributor.authorPinto, Elmano
dc.contributor.authorTaboada, Bruna Rafaela Pereira
dc.contributor.authorFaustino, Vera
dc.contributor.authorCidre, Diana
dc.contributor.authorRodrigues, Raquel Oliveira
dc.contributor.authorMiranda, João Mário
dc.contributor.authorGarcia, Valdemar
dc.contributor.authorDias, Ricardo P.
dc.contributor.authorLima, Rui A.
dc.date.accessioned2013-09-12T12:04:42Z
dc.date.available2013-09-12T12:04:42Z
dc.date.issued2013
dc.description.abstractThe xurography is a technique that has been used to make molds to produce microchannels. In contrast to soft lithography [1, 2], xurography uses equipments and materials commonly used in the printing industry, such as cutting plotters, vinyl and other materials. The main advantage of this technique is to fabricate microchannels at a reduced cost [3, 4]. The Fahraeus-Lindqvist effect is a well know phenomenon that happens in microcirculation, where red blood cells (RBCs) have tendency to migrate toward the centre of the microtube resulting in a marginal cell-free layer (CFL) at regions adjacent to the wall [5]. Recently several studies showed strong evidence that the formation of the CFL is affected by the geometry of the microchannel [1, 6, 7] and the physiological conditions of the working fluid, such as the hematocrit (Hct) [2, 8]. The main objective of the present work is to fabricate polydimethysiloxane (PDMS) microchannels by using a soft xurography technique in order perform blood flow studies. Additionally, a high-speed video microscopy system is used to measure the CFL thickness in two different geometries, i. e., bifurcations and confluences.por
dc.identifier.citationPinto, E.; Taboada, B.; Faustino, V.; Cidre, D.; Rodrigues, R.; Miranda, J.; Garcia, V.; Dias, Ricardo; Lima, R. (2013). Blood flow in microchannels manufactured by a low cost technique: xurography. In Eds. Rubio-Hernández F. J. [et al.] Perspectives in Fundamental and Applied Rheology. Gráficas Fernando. p. 285-290. ISBN 978-84-616-5245-7por
dc.identifier.isbn978-84-616-5245-7
dc.identifier.urihttp://hdl.handle.net/10198/8738
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationANEURYSM - Hemodynamic Study in Cerebral Aneurysms
dc.relationBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
dc.subjectBlood flowpor
dc.subjectXurograpgypor
dc.subjectCell free layerpor
dc.subjectBifurcationspor
dc.titleBlood flow in microchannels manufactured by a low cost technique: xurographypor
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleANEURYSM - Hemodynamic Study in Cerebral Aneurysms
oaire.awardTitleBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FEME-MFE%2F099109%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-ENB%2F116929%2F2010/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-BEB%2F105650%2F2008/PT
oaire.citation.titlePerspectives in Fundamental and Applied Rheologypor
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
person.familyNameGarcia
person.familyNameDias
person.familyNameLima
person.givenNameValdemar
person.givenNameRicardo P.
person.givenNameRui A.
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0002-3941-2438
person.identifier.orcid0000-0003-1503-998X
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id7102885151
person.identifier.scopus-author-id18437397800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typebookPartpor
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