| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 325.11 KB | Adobe PDF |
Advisor(s)
Abstract(s)
The European hackberry (Celtis australis L.) is a deciduous tree of the Cannabaceae
family frequently found in southern Europe and western Asia. Its fruit is an edible,
dark-purple berry-like drupe with a large seed that corresponds to about 38% of the
fruit dry weight [ l ]. Fruit preparations are used in traditional medicine as a remedy for
colic, peptic ulcers, dysentery, diarrhea, amenorrhea, and heavy menstrual bleeding
[1-3]. However, as far as we know, the antioxidant and antimicrobial properties of C.
australis seeds have never been explored before, being this the purpose ofthis study.
The C. australis seed extract was obtained by a solid-liquid extraction of the powdered
sample with methanol water (80:20, v/v) [4]. Then, the antioxidant activity was
measured in vitro via DPPH' scavenging activity, reducing power, p-carotene bleaching
inhibition capacity, and thiobarbituric acid reactive substances (TBARS) formation
inhibition capacity in brain cell homogenates [4]. The antimicrobial activity was
screened against twelve microorganisms, including Gram-positive and Gram-negative
bactéria and fungi, by the microdilution method [5].
The seed extract was effective in inhibiting the formation of TBARS as byproducts
Of lipid peroxidation, which was concluded from the low EC^ value. The extract also
had an interesting reducing power and capacity to protect p-carotene from the free
radicais generated from linoleic acid. Regarding its antimicrobial activity, the best
results were against B. cereus, with MIC and MBC lower than ampicillin, A. ochraceus,
with MIC and MFC lower than ketoconazole, and P. funiculosum, with MIC lower
than ketoconazole and bifonazole and MFC lower than ketoconazole.
These results highlighted the potential of C. australis seeds as an interesting fruit byproduct
to be used in the development of bio-based antimicrobials.
Description
Keywords
European hackberry Celtis australís L.
Pedagogical Context
Citation
Alonso-Esteban, José Ignacio; Pinela, José; Soković, Marina; Barros, Lillian; Sánchez-Mata, Maria Cortes; Torija-Isasa, Esperanza; Ferreira, Isabel C.F.R. (2018). Antioxidant and antimicrobial activities of European hackberry (Celtis australis L.) seeds. In XXIV Encontro Luso Galego de Química. Porto. ISBN 978-989-8124-24-1