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The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: results of a multicenter randomized controlled trial (ERIC-HF study)

2022Artigo científico Acesso aberto
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dc.contributor.authorDelgado, Bruno
dc.contributor.authorNovo, André
dc.contributor.authorLopes, Ivo
dc.contributor.authorRebelo, Carina
dc.contributor.authorAlmeida, Cecília
dc.contributor.authorPestana, Sandra
dc.contributor.authorGomes, Bárbara
dc.contributor.authorFroelicher, Erika
dc.contributor.authorKlompstra, Leonie
dc.date.accessioned2022-03-24T14:11:39Z
dc.date.available2022-03-24T14:11:39Z
dc.date.issued2022
dc.description.abstractTo analyze (1) the effect of an aerobic training program on functional exercise tolerance in decompensated heart failure (DHF) patients; (2) to assess the effects of an aerobic training program on functional independence; and (3) dyspnea during activities of daily living. Design A randomized controlled clinical trial with follow-up at discharge. Settings Eight hospitals. Recruitment took place between 9/ 2017 and 3/2019. Group Assignments Patients with DHF who were admitted to the hospital, were randomly assigned to usual rehabilitation care guideline recommended (control group) or aerobic training program (exercise group). Main outcome Functional exercise tolerance was measured with a 6-min walking test at discharge. Results In total 257 patients with DHF were included, with a mean age of 67 ± 11 years, 84% (n = 205) had a reduced ejection fraction and the hospital stay was 16 ± 10 days. At discharge, patients in the intervention group walked further compared to the control group (278 ± 117m vs 219 ± 115m, p < 0.01) and this difference stayed significant after correcting for confounders (p < 0.01). A significant difference was found favoring the exercise group in functional independence (96 ± 7 vs 93 ± 12, p = 0.02) and dyspnea associated to ADL (13 ± 5 vs 17 ± 7, p < 0.01) and these differences persisted after correcting for baseline values and confounders (functional independence p < 0.01; dyspnea associated with ADL p = 0.02). Conclusion The ERIC-HF program is safe, feasible, and effective in increasing functional exercise tolerance and functional independence in hospitalized patients admitted due to DHF.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDelgado, Bruno; Novo, André; Lopes, Ivo; Rebelo, Carina; Almeida, Cecília; Pestana, Sandra; Gomes, Bárbara; Froelicher, Erika; Klompstra, Leonie (2022). The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: results of a multicenter randomized controlled trial (ERIC-HF study). Clinical Rehabilitation. ISSN 1477-0873. 36:6, p. 813-821pt_PT
dc.identifier.doi10.1177/02692155221088684
dc.identifier.issn1477-0873
dc.identifier.urihttp://hdl.handle.net/10198/25283
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSage Journalspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFunctional exercise tolerancept_PT
dc.subjectActivities of daily livingpt_PT
dc.subjectHeart diseasespt_PT
dc.subjectFunctional independencept_PT
dc.subjectHeart failurept_PT
dc.titleThe effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: results of a multicenter randomized controlled trial (ERIC-HF study)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage9pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleClinical Rehabilitationpt_PT
person.familyNameNovo
person.givenNameAndré
person.identifierH-1386-2012
person.identifier.ciencia-id7D14-8584-AB2B
person.identifier.orcid0000-0001-8583-0406
person.identifier.scopus-author-id612710
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf17cfa22-2a97-4396-bdc6-4570baee6885
relation.isAuthorOfPublication.latestForDiscoveryf17cfa22-2a97-4396-bdc6-4570baee6885

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