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Advisor(s)
Abstract(s)
The population aged ≥60 years is growing worldwide. The World Health Organization
(WHO) reported that the elderly population is expected to increase from 1 billion in 2020 to
1.4 billion in 2030 and 2.1 billion in 2050 (World Health Organization, 2022). This increase
in life expectancy around the globe is accompanied with the enhancing frequency of agingassociated
disorders, mainly due to the deterioration of metabolic, circulatory, and immune
functioning. Inflammaging (chronic low-grade inflammation) is considered as one of the
main drivers of the initiation and progression of diseases such as sarcopenia, osteoporosis,
metabolic ailments, atherosclerosis, neurodegenerations, and carcinogenesis (Ullah et al.,
2022). However, the actual etiology of these disorders is complicated due to the complex
interaction of genes and environment, making their management more challenging in realworld
circumstances. Currently, pharmacological interventions remained the mainstream
option for the treatment of age-related diseases although drugs are associated with increased
risk of the occurrence of adverse effects due to the increased susceptibility of adult
population to drug effects, altered pharmacokinetic parameters, and use of
polypharmacy, which may also increase the likelihood of drug interactions (Baldoni
et al., 2010; Goldberg et al., 2022; Kwak et al., 2022).
Description
Keywords
Natural products Herbal medicines (HM) Aging Age related disorders Prevention
Citation
Ullah, Hammad; Khan, Haroon; Prieto Lage, Miguel A.; Daglia, Maria (2024) Editorial: Herbal medical products and natural products targeting aging and age-related disorders-ethnopharmacological perspectives. Frontiers in Pharmacology. EISSN 1663-9812. 15, p. 1-3
Publisher
Frontiers