Publication
Determination of the cell-free layer in circular PDMS microchannels
| dc.contributor.author | Cerdeira, Tânia Filipa Alves | |
| dc.contributor.author | Lima, Rui A. | |
| dc.contributor.author | Oliveira, Mónica | |
| dc.contributor.author | Monteiro, Fernando C. | |
| dc.contributor.author | Ishikawa, Takuji | |
| dc.contributor.author | Imai, Yohsuke | |
| dc.contributor.author | Yamaguchi, Takami | |
| dc.date.accessioned | 2011-06-09T15:45:28Z | |
| dc.date.available | 2011-06-09T15:45:28Z | |
| dc.date.issued | 2010 | |
| dc.description.abstract | In microcirculation the cell-free layer is believed to reduce the friction between red blood cells (RBCs) and endothelial cells and consequently reduce blood flow resistance. However, the complex formation of the cell-free layer has not yet been convincingly described mainly due to multi-physical and hemorheological factors that affect this phenomenon. In this experimental work, we study the effect of hematocrit (Hct) on the thickness of the cell-free layer in straight circular polydimethylsiloxane (PDMS) microchannels. The channels studied are 73 ± 2 mm in diameter, flexible and circular to mimic blood vessels. The images are captured using confocal microscopy and are post-processed using Image J and MATLAB. The formation of a cell-free layer is clearly visible in the images captured and by using a combination of image analysis techniques we are able to detect an increase in the cell-free layer thickness as Hct decreases. | por |
| dc.identifier.citation | Cerdeira, T.; Lima, R.; Oliveira, M.; Monteiro, Fernando C.; Ishikawa, T.; Imai, Y.; Yamaguchi, T. (2010). Determination of the cell-free layer in circular PDMS microchannels. In COMPUTATIONAL VISION AND MEDICAL IMAGING PROCESSING VIP Image. Porto. ISBN 978-0-415-57041-1. | por |
| dc.identifier.isbn | 978-0-415-57041-1 | |
| dc.identifier.uri | http://hdl.handle.net/10198/5103 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Taylor and Francis | por |
| dc.subject | Cell-free layer | por |
| dc.subject | Microchannels | por |
| dc.title | Determination of the cell-free layer in circular PDMS microchannels | por |
| dc.type | conference paper | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Porto | por |
| oaire.citation.title | COMPUTATIONAL VISION AND MEDICAL IMAGING PROCESSING VIP Image 2009 | por |
| person.familyName | Lima | |
| person.familyName | Monteiro | |
| person.givenName | Rui A. | |
| person.givenName | Fernando C. | |
| person.identifier.ciencia-id | EE12-C3FB-349D | |
| person.identifier.ciencia-id | 2019-BDBF-10E2 | |
| person.identifier.orcid | 0000-0003-3428-637X | |
| person.identifier.orcid | 0000-0002-1421-8006 | |
| person.identifier.rid | H-5157-2016 | |
| person.identifier.rid | H-9213-2016 | |
| person.identifier.scopus-author-id | 18437397800 | |
| person.identifier.scopus-author-id | 8986162600 | |
| rcaap.rights | openAccess | por |
| rcaap.type | conferenceObject | por |
| relation.isAuthorOfPublication | 7b50c499-8095-4f4f-8b1b-fa7388e4ff62 | |
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