Sanguisorba officinalis L., an alternative source of phenolic compounds and remarkable bioactivities

Finimundy, Tiane C.; Karkanis, Anestis; Petropoulos, Spyridon Α.; Fernandes, Ângela; Calhelha, Ricardo C.; Barros, Lillian; Rosa, Eduardo; Ferreira, Isabel C.F.R.

http://hdl.handle.net/10198/24916

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Authors

Finimundy, Tiane C.

Karkanis, Anestis

Petropoulos, Spyridon Α.

Ferreira, Isabel C.F.R.

Abstract(s)

Sanguisorba officinalis L. or great burnet, belongs to the Rosaceae family and it is a perennial plant widely distributed throughout Europe,Asia and North America (1). It is well known as a traditional herbal medicine due to its bioactive compounds content (2). This study aimed to evaluate the phenolic profile and bioactives of leaves and roots od S. officinalis plants were cultivated in central Greece, using different types of fertilizers, namely: i) control - without fertilization (A: leaves; B: roots); ii) inorganic fertilizer at a rate of 330 kg/ha (C: leaves; D: roots); and iii) inorganic fertilizer at a rate 660kg/ha (E: leaves; F: roots): Phenolic compounds were identified and quantified by HPLC-DAD-ESI/MSn. Four Gram-negative and four Gram-positive bacteria, and six fungi were used to screen the antimicrobial activity of the samples. Cytotoxic activity was tested on tumor cell lines of MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer), HeLa (cervical carcinoma), HepG2 (hepatocellular carcinoma) and a non-tumor cell line (PLP2).

URI

http://hdl.handle.net/10198/24916

Citation

Finimundy, Tiane C.; Karkanis, Anestis; Petropoulos, Spyridon A.; Fernandes, Ângela; Calhelha, Ricardo; Barros, Lillian; Rosa, Eduardo; Ferreira, Isabel C.F.R. (2021). Sanguisorba officinalis L., an alternative source of phenolic compounds and remarkable bioactivities. In IberPhenol international Conference. Coimbra