Publication
Antioxidant activity and cytotoxic effects of polar extracts from saffron (Crocus sativus L.) flowers
| dc.contributor.author | Barreira, João C.M. | |
| dc.contributor.author | Rebelo, José Miguel | |
| dc.contributor.author | Costa, Carla Sofia | |
| dc.contributor.author | Costa, Anabela S.G. | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.contributor.author | Teixeira, João Paulo Fernandes | |
| dc.contributor.author | Oliveira, Beatriz | |
| dc.date.accessioned | 2015-11-30T15:06:16Z | |
| dc.date.available | 2015-11-30T15:06:16Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Saffron is cultivated exclusively to obtain the stigma of its flowers, which represents less than 10% of the flower weight. In fact, to achieve a single kg of dried stigma, more than 60 kg of floral bio-residues are produced. These bio-residues were reported as having high bioactivity and important contents in bioactive compounds. Before considering the use of these bioresidues in different applications, it is important to assess its cytotoxicity. Herein, the antioxidant activity and cytotoxicity of saffron flower polar extracts were evaluated. All samples showed antioxidant activity, despite the higher effectiveness of the hydroalcoholic extract. Up to the concentrations corresponding to the EC50 values obtained in the antioxidant activity assays, none of the extracts showed high cytotoxicity against Caco-2 cell lines. Accordingly, saffron flowers might be used in different applications such as the development of food supplements or pharmaceutical related products. | pt_PT |
| dc.identifier.citation | Barreira, João C.M.; Rebelo, José Miguel; Costa, Carla; Costa, Anabela S.G.; Ferreira, Isabel C.F.R.; Teixeira, João P.; Oliveira, M.B.P.P. (2014). Antioxidant activity and cytotoxic effects of polar extracts from saffron (Crocus sativus L) flowers. In 12º Encontro de Química dos Alimentos. Lisboa. p. 320-323 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10198/12456 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.relation | Strategic Project - UI 690 - 2011-2012 | |
| dc.relation | Strategic Project - LA 6 - 2011-2012 | |
| dc.relation | Impact of transplacental exposure to tobacco smoke in the DNA of newborn. Evaluation of genetic damage and epigenetic changes. Evolution throughout childhood. | |
| dc.relation | BIOACTIVE PROPERTIES & CYTOPROTECTIVE POTENTIAL OF NATURAL EXTRACTS/INDIVIDUAL COMPOUNDS: APPLICATION OF SINGLE CELL GEL ELECTROPHORESIS AND OTHER BIOCHEMICAL, CHEMICAL AND ELECTROCHEMICAL ASSAYS | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Crocus sativus | pt_PT |
| dc.subject | Antioxidant activity | pt_PT |
| dc.subject | Citotoxicity | pt_PT |
| dc.title | Antioxidant activity and cytotoxic effects of polar extracts from saffron (Crocus sativus L.) flowers | pt_PT |
| dc.type | conference paper | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Strategic Project - UI 690 - 2011-2012 | |
| oaire.awardTitle | Strategic Project - LA 6 - 2011-2012 | |
| oaire.awardTitle | Impact of transplacental exposure to tobacco smoke in the DNA of newborn. Evaluation of genetic damage and epigenetic changes. Evolution throughout childhood. | |
| oaire.awardTitle | BIOACTIVE PROPERTIES & CYTOPROTECTIVE POTENTIAL OF NATURAL EXTRACTS/INDIVIDUAL COMPOUNDS: APPLICATION OF SINGLE CELL GEL ELECTROPHORESIS AND OTHER BIOCHEMICAL, CHEMICAL AND ELECTROCHEMICAL ASSAYS | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FEQB%2FLA0006%2F2011/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F96196%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F72802%2F2010/PT | |
| oaire.citation.endPage | 323 | pt_PT |
| oaire.citation.startPage | 320 | pt_PT |
| oaire.citation.title | 12º Encontro de Química dos Alimentos, 10 a 12 de setembro de 2014 | pt_PT |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6820 - DCRRNI ID | |
| person.familyName | Barreira | |
| person.familyName | Ferreira | |
| person.givenName | João C.M. | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0003-1233-0990 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | D-8269-2013 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 54895546900 | |
| person.identifier.scopus-author-id | 36868826600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isAuthorOfPublication | 4629b12c-39b0-4da8-8b8d-6efba5cf2d81 | |
| relation.isAuthorOfPublication | bd0d1537-2e03-41fb-b27a-140af9c35db8 | |
| relation.isAuthorOfPublication.latestForDiscovery | bd0d1537-2e03-41fb-b27a-140af9c35db8 | |
| relation.isProjectOfPublication | c59f09d4-9931-4f2e-babb-ef8bed998be7 | |
| relation.isProjectOfPublication | c40e3666-1466-44a3-b595-b3c38d27fa0b | |
| relation.isProjectOfPublication | e6edaabc-d088-4500-b27a-2cf2f7d657c7 | |
| relation.isProjectOfPublication | 3ff07254-7d34-46ec-a291-9228bc17eac4 | |
| relation.isProjectOfPublication.latestForDiscovery | c40e3666-1466-44a3-b595-b3c38d27fa0b |