Extraction of Bioactive Compounds from Rubus Idaeus Bioresidues: A Full Screening on Phenolic Composition and Bioactive Potential

Purpose Rubus idaeus cultivation has boosted productivity due to its high nutritional value. In consequence, waste produc- tion increased. The discarded biomass, including leaves and aerial components, can be transformed into valuable functional ingredients for industrial applications, such as cosmetics. Studying their bioactivity potential is highly relevant. Methods According to the present idea, the research involved producing extracts from raspberry plant branches and leaves by employing four different techniques: aqueous decoction, aqueous infusion, hydroethanolic maceration, and ultrasound- assisted extraction (UAE). Subsequently, these compounds were screened for their bioactive potential, including antioxidant, antibacterial, anti-inflammatory, and cytotoxic properties. Results The ultrasound-assisted extraction produced extracts rich in phenolic compounds, whereas the infusion and macera- tion methods resulted in higher flavonol contents. Among the identified phenolic compounds, hydrolyzable tannins, particu- larly galloyl-bis-HHDP-glucose, were the most dominant ones. Regarding antioxidant potential, the decoction extract was the strongest, while the infusion showed the greatest potential for inhibiting lipid peroxidation. The UAE extract was found to be highly effective as an antibacterial agent. Both infusion and UAE extracts demonstrated the highest anti-inflammatory potential. Conclusion The combination of these results highlights the sample’s bioactive potential and the importance of exploiting bioresidues as unique, sustainable candidates for industrial applications.

Keywords

Added valuable compounds Biological activity Extraction technologies Low economic raw material

URI

http://hdl.handle.net/10198/34393

Citation

Plasencia, Paula; Finimundy, Tiane Cristine; Carocho, Márcio; Calhelha, Ricardo C.; Añibarro Ortega, Mikel; Pires, Tânia C.S.P.; Barreiro, Filomena; Garcia, Pablo A.; Barros, Lillian; Heleno, Sandrina A. (2024). Extraction of Bioactive Compounds from Rubus Idaeus Bioresidues: A Full Screening on Phenolic Composition and Bioactive Potential. Waste and Biomass Valorization. ISSN 1877-2641. 16:2, p. 737–747