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Antioxidant and anti-inflammatory activities of cytisus multiflorus

2012Conference poster Open access
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dc.contributor.authorSaraiva, Susana C.
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorLiberal, Joana
dc.contributor.authorBatista, Maria T.
dc.contributor.authorDomingues, Maria R.M.
dc.contributor.authorCruz, Maria T.
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2012-10-09T15:14:54Z
dc.date.available2012-10-09T15:14:54Z
dc.date.issued2012
dc.description.abstractCytisus multiflorus(white spanish broom) is a plant used in folk medicine in the Iberian Peninsula, where it is claimed to have various health benefits. However, the usage is totally based on the available ethnopharmacological information, as no scientific data regarding its biological effects has been delivered. In this sense, is the aim of this work to contribute to the scientific knowledge of the antioxidant and anti-inflammatory properties of C. multiflorus. The extract was rich in phenolic compounds mainly chrysin-7-O-glycopyranoside and a dihydroxyflavone isomer of chrysin which accounted for 49.4±7.3 mg/g and 21.8±3.8 mg/g, respectively. The low EC50 values, determined by DPPH and reducing power assays, indicated that the C. multiflorus purified ethanolic extract has a high antioxidant capacity. Moreover, the extract did not cause cytotoxicity against RAW 264.7 macrophages for high concentrations and the treatment of this cell line with purified extract induced a significant decrease in the levels of NO. Overall, the gathered data suggests that C. multiflorus is in fact a good antioxidant and anti-inflammatory plant, as believed by the folk knowledge.por
dc.identifier.citationSaraiva, Susana C.; Pereira, Olívia R.; Liberal, Joana; Batista, Maria T.; Domingues, Maria R. M.; Cruz, Maria T.; Cardoso, Susana M. (2012). Antioxidant and anti-inflammatory activities of Cytisus multiflorus. In Conferência Centro de Estudos Farmacêuticos 2012. Coimbrapor
dc.identifier.urihttp://hdl.handle.net/10198/7616
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherCentro Estudos Farmacêuticospor
dc.relation.publisherversionhttp://www.ff.uc.pt/cef2012/home/por
dc.subjectCytisus multifloruspor
dc.subjectPhenolic compoundspor
dc.subjectAntioxidant capacitypor
dc.subjectAntiinflamatory activitypor
dc.titleAntioxidant and anti-inflammatory activities of cytisus multifloruspor
dc.typeconference poster
dspace.entity.typePublication
oaire.citation.conferencePlaceCoimbrapor
oaire.citation.titleConferência Centro de Estudos Farmacêuticos 2012por
person.familyNamePereira
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453

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