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Velocity fields of blood flow in microchannels using a confocal micro-PIV system

dc.contributor.authorLima, Rui A.
dc.contributor.authorIshikawa, Takuji
dc.contributor.authorTanaka, Shuji
dc.contributor.authorTakeda, Motohiro
dc.contributor.authorTsubota, Ken-ichi
dc.contributor.authorWada, Shigeo
dc.contributor.authorYamaguchi, Takami
dc.date.accessioned2010-01-30T14:33:54Z
dc.date.available2010-01-30T14:33:54Z
dc.date.issued2007
dc.description.abstractThe in vitro experimental investigations provide an excellent approach to understand complex blood flow phenomena involved at a microscopic level. This paper emphasizes an emerging experimental technique capable to quantify the flow patterns inside microchannels with high spatial and temporal resolution. This technique, known as confocal micro-PIV, consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser. Velocity profiles of pure water (PW), physiological saline (PS) and in vitro blood were measured in a 100mm glass square and rectangular polydimethysiloxane (PDMS) microchannel. The good agreement obtained between measured and estimated results suggests that this system is a very promising technique to obtain detail information about micro-scale effects in microchannels by using both homogeneous and non-homogeneous fluids such as blood flow.pt
dc.description.sponsorshipThis study was supported in part by the following grants: 21st Century COE Program for Future Medical Engineering based on Bio-nanotechnology, International Doctoral Program in Engineering from the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT), “Revolutionary Simulation Software (RSS21)” next-generation IT program of MEXT; Grants-in-Aid for Scientific Research from MEXT and JSPS Scientific Research in Priority Areas (768) “Biomechanics at Micro- and Nanoscale Levels,” Scientific Research (A) No.16200031 “Mechanism of the formation, destruction, and movement of thrombi responsible for ischemia of vital organs.” The authors also thank all members of Esashi, Ono and Tanaka Lab. for their assistance in fabricating the PDMS microchannel.
dc.identifier.citationLima, R.; Ishikawa, T.; Tanaka, S.; Takeda, M.; Tsubota, K.; Wada, S.; Yamaguchi, T. (2007). Velocity fields of blood flow in microchannels using a confocal micro-PIV system. In 9th International Symposium on Future Medical Engineering Based on Bionanotechnology. Future medical engineering based on Bionanotechnology. p. 311-316.pt
dc.identifier.doi10.1142/9781860948800_0104
dc.identifier.urihttp://hdl.handle.net/10198/1580
dc.language.isoengpt
dc.peerreviewedyes
dc.publisherWorld Scientificpt
dc.subjectMicrochannelpt
dc.subjectMicrocirculationpt
dc.subjectConfocal micro-PIVpt
dc.subjectBlood flowpt
dc.titleVelocity fields of blood flow in microchannels using a confocal micro-PIV systempt
dc.typeconference paper
dspace.entity.typePublication
oaire.citation.endPage316pt
oaire.citation.startPage311pt
oaire.citation.titleFuture Medical Engineering based on Bio-nanotechnologypt
person.familyNameLima
person.givenNameRui A.
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id18437397800
rcaap.rightsopenAccesspt
rcaap.typeconferenceObjectpt
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication.latestForDiscovery7b50c499-8095-4f4f-8b1b-fa7388e4ff62

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