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Advisor(s)
Abstract(s)
The in vitro experimental investigations provide an excellent approach to understand
complex blood flow phenomena involved at a microscopic level. This paper emphasizes
an emerging experimental technique capable to quantify the flow patterns inside
microchannels with high spatial and temporal resolution. This technique, known as
confocal micro-PIV, consists of a spinning disk confocal microscope, high speed camera
and a diode-pumped solid state (DPSS) laser. Velocity profiles of pure water (PW),
physiological saline (PS) and in vitro blood were measured in a 100mm glass square and
rectangular polydimethysiloxane (PDMS) microchannel. The good agreement obtained
between measured and estimated results suggests that this system is a very promising
technique to obtain detail information about micro-scale effects in microchannels by
using both homogeneous and non-homogeneous fluids such as blood flow.
Description
Keywords
Microchannel Microcirculation Confocal micro-PIV Blood flow
Citation
Lima, R.; Ishikawa, T.; Tanaka, S.; Takeda, M.; Tsubota, K.; Wada, S.; Yamaguchi, T. (2007). Velocity fields of blood flow in microchannels using a confocal micro-PIV system. In 9th International Symposium on Future Medical Engineering Based on Bionanotechnology. Future medical engineering based on Bionanotechnology. p. 311-316.
Publisher
World Scientific