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Sensibility and specificity analysis for waist-to-height ratio, body mass index and waist circumference as a screening criterion for metabolic syndrome in an adult North-East Portuguese population

2022Conference object Open access
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dc.contributor.authorTeixeira, José Eduardo
dc.contributor.authorBragada, José A.
dc.contributor.authorBragada, João P.
dc.contributor.authorCoelho, Joana C.M.M.
dc.contributor.authorPinto, Isabel
dc.contributor.authorReis, Luís P.
dc.contributor.authorSaldanha, Laissa de Sousa
dc.contributor.authorDuarte, Carlos Manuel Teixeira
dc.contributor.authorMagalhães, Pedro
dc.date.accessioned2022-07-21T14:29:03Z
dc.date.available2022-07-21T14:29:03Z
dc.date.issued2022
dc.description.abstractObesity is a central component of Metabolic Syndrome (MetS) and a major public health concern. A harmonizing MetS definition was developed to aggregate the different criteria used by the umbrella organizations, however there is still controversy over the most sensitive and specific parameter to characterize each MetS component. The aim of this study was to compare the sensibility and specificity for waist-toheight ratio (WHtR), body mass index (BMI) and waist circumference (WC) to discriminate subjects with and without MetS in an adult North-East Portuguese population. Methods: A cross-sectional retrospective analysis was conducted between January 2019 and December 2020 from patients’ clinical records of two primary health care centers in a North-East Portuguese region. A total of 6570 individuals aged 18–102 years were included for analysis, among which 3865 women (57.37±18.67 years) and 2705 men (59.97±16.76 years). MetS was defined according to HARM2009 statement set by Alberti et al. (2009). Standardized cut-off points were used to measure WHtR (≥0.5), BMI (≥30 kg/m2) and WC (>88 cm in women and >102 cm in men). A binary logistic regression was performed for the areas under receiver operating characteristic curves (AUC) and adjusted odd ratios (OR) with a 95% confidence interval (CI). Results: MetS was present in 3,581 (54.51%) subjects, where 1,914 (49,52%) were women and 1,667 (61.63%) men. AUC demonstrated that WHtR was significantly more powerful than WC and BMI (p<0.05) for screening MetS (AUCWHtR = 0.785, 95% CI: 0.774–0.796; AUCWC = 0.768, 95% CI: 0.757–0.779; AUCBMI = 0.751, 95% CI: 0.703–0.796). Men are 1.53 (95% CI: 1.37–1.72, p<0.001) times more likely of having MetS compared to women. Also, the discriminative power of the three criteria for predicting MetS is higher in men (AUCWHtR = 0.795, 95% CI: 0.778–0.812; AUCWC = 0.783, 95% CI: 0.766–0.801; AUCBMI = 0.740, 95% CI: 0.722–0.759) than women (AUCWHtR = 0.782, 95% CI: 0.768–0.797; AUCWC = 0.760, 95% CI: 0.744–0.775; AUCBMI = 0.699, 95% CI: 0.683–0.716). However, WHtR is still the most powerfull screening criterion for MetS in both sexes. Conclusion: Adjusting individual’s waist circumference to height revealed a greater sensitivity and specificity for MetS screening than isolated WC and BMI. Current research suggests that WHtR is as a better predictor for MetS, specifically in its obesity component.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTeixeira, José Eduardo; Bragada, José A.; Bragada, João; Coelho, Joana; Pinto, Isabel; Reis, Luís; Saldanha, Laissa; Duarte, Carlos; Magalhães, Pedro (2022). Sensibility and specificity analysis for waist-to-height ratio, body mass index and waist circumference as a screening criterion for metabolic syndrome in an adult North-East Portuguese population. In ZoomForward2022: European Congress on Obesity. Obesity Facts. ISSN 1662-4025. 15(suppl 1), p. 210–211pt_PT
dc.identifier.issn1662-4025
dc.identifier.urihttp://hdl.handle.net/10198/25713
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectObesitypt_PT
dc.titleSensibility and specificity analysis for waist-to-height ratio, body mass index and waist circumference as a screening criterion for metabolic syndrome in an adult North-East Portuguese populationpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMaastrichtpt_PT
oaire.citation.endPage211pt_PT
oaire.citation.issueSuppl. 1pt_PT
oaire.citation.startPage210pt_PT
oaire.citation.titleObesity Factspt_PT
oaire.citation.volume15pt_PT
person.familyNameTeixeira
person.familyNameBragada
person.familyNameMagalhães
person.givenNameJosé Eduardo
person.givenNameJosé A.
person.givenNamePedro
person.identifier2316939
person.identifier.ciencia-idD11C-9591-7A8A
person.identifier.ciencia-idEC18-B34C-A1C8
person.identifier.ciencia-id631D-E634-0FBB
person.identifier.orcid0000-0003-4612-3623
person.identifier.orcid0000-0001-7020-0583
person.identifier.orcid0000-0003-2492-1499
person.identifier.scopus-author-id35224896200
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication79042f92-ce53-4b79-a33f-76ac63c55b8d
relation.isAuthorOfPublicationd24f0ee1-6174-4249-8e0a-20629d306235
relation.isAuthorOfPublicationce33c577-a21a-4f32-9443-ea36d0af8d72
relation.isAuthorOfPublication.latestForDiscoveryd24f0ee1-6174-4249-8e0a-20629d306235

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