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Title: Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
Authors: Ferreira, Isabel C.F.R.
Queiroz, Maria João R.P.
Vilas-Boas, Miguel
Estevinho, Leticia M.
Begouin, Agathe
Kirsch, Gilbert
Keywords: Diarylamines
Antioxidant activity
Structure–activity relationships
Issue Date: 2006
Publisher: Elsevier
Citation: Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 16:5 (2006) p. 1384-1387
Abstract: The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure–activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO2Et, CO2H).
ISSN: 0960-894X
Appears in Collections:BB - Artigos em Revistas Indexados ao ISI/Scopus

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