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Advisor(s)
Abstract(s)
Chemical composition of the essential oils (EO) of Pelargonium graveolens,
Leptospermum petersonii and Cymbopogon martinii var. motia, and the
absolute of Rosa centifolia and their bioactivity were examined. Major compounds
in P. graveolens EO were monoterpene alcohols citronellol, geraniol and
linalool; in L. petersonii EO monoterpene aldehydes geranial, neral and citronellal;
in C. martiniii var. motia EO monoterpene alcohol geraniol and ester
geranyl acetate, while in absolute of R. centifolia aromatic alcohol 2-phenylethanol.
The EO of L. petersonii showed the strongest antibacterial while the EO of
C. martinii var. motia the strongest antifungal potential. The best biofilm inhibition
capacity was observed with R. centifolia absolute. The results of scanning
electron microscopy analysis indicated that the EOs of L. petersonii and P.
graveolens changed the number and morphology of C. albicans cells. The L.
petersonii EO was the most potent toward tumour cells and exhibited the best
biological activity. This is first comparative report summarizing efficacy of studied
aromatic samples against pathogenic microbes, providing deeper insight into
the modes of antimicrobial action, and at the same time describing their cytotoxicity
against cell lines.
Description
Keywords
Volatiles Antibacterial effect Anticandidal activity Cytotoxic Antibiofilm SEM
Pedagogical Context
Citation
Nikolic, Milos; Markovic, Tatjana; Markovic, Dejan; Calhelha, Ricardo;Fernandes, Ângela; Ferreira, Isabel C.F.R.; Stojkovic, Dejan; Ciric, Ana; Glamoclija, Jasmina; Sokovic, Marina (2021). Chemical composition and biological properties of Pelargonium graveolens, Leptospermum petersonii and Cymbopogon martinii var. motia essential oils and of Rosa centifolia absolute. Journal of the Serbian Chemical Society. ISSN 1820-7421. 86:12, p. 1291-1303