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An in vitro study of the origanum minutiflorum O. Schwarz & P. H. Davis and Coriandrum sativum L. essential oils as chronic tonsillitis therapeutics: antibacterial, antibiofilm, antioxidant, and cytotoxic activities

dc.contributor.authorKostić, Marina
dc.contributor.authorIvanov, Marija
dc.contributor.authorMarković, Tatjana
dc.contributor.authorSankovic-Babic, Snezana
dc.contributor.authorBarros, Lillian
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorSoković, Marina
dc.contributor.authorCirić, Ana
dc.date.accessioned2023-01-17T12:01:19Z
dc.date.available2023-01-17T12:01:19Z
dc.date.issued2022
dc.description.abstractThe chemical composition and biological activity of essential oils (EOs) from leaves of Origanum minutiflorum O. Schwarz & P.H.Davis, and seeds of Coriandrum sativum L. were investigated. Chemical analyses of EOs were performed and the major components were carvacrol (81.5%) and linalool (69.6%), respectively. The antimicrobial activity was assessed against several bacteria originating from the tonsillar tissue. Activities of EOs against Staphylococcus aureus biofilm were investigated, as well as the effect of the mixture of these EOs and antibiotics against the pathogen. The antioxidant activity of both EOs was determined by TBARS assay, and examined wild oregano EO showed better activity. Also, cytotoxicity of EOs was evaluated in vitro and both EOs showed potential to inhibit further proliferation of tumor cells. This study reported for the first time the effects of EOs on chronic tonsillitis causative pathogens, supporting their role as a natural bioactive therapeutic agent with possible antimicrobial applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationKostić, Marina; Ivanov, Marija; Marković, Tatjana; Sankovic-Babic, Snezana; Barros, Lillian; Calhelha, Ricardo C.; Soković, Marina; Cirić, Ana. (2022). An in vitro study of the origanum minutiflorum O. Schwarz & P. H. Davis and Coriandrum sativum L. essential oils as chronic tonsillitis therapeutics: antibacterial, antibiofilm, antioxidant, and cytotoxic activities. Computation. EISSN 2163-8152. 34:6, p. 1-12pt_PT
dc.identifier.doi10.3390/computation10060091pt_PT
dc.identifier.eissn2163-8152
dc.identifier.urihttp://hdl.handle.net/10198/26564
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectWild oregano leaf oilpt_PT
dc.subjectCoriander seed oilpt_PT
dc.subjectInfectionspt_PT
dc.subjectStaphylococcus aureuspt_PT
dc.subjectCytotoxicitypt_PT
dc.titleAn in vitro study of the origanum minutiflorum O. Schwarz & P. H. Davis and Coriandrum sativum L. essential oils as chronic tonsillitis therapeutics: antibacterial, antibiofilm, antioxidant, and cytotoxic activitiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleComputationpt_PT
person.familyNameBarros
person.familyNameCalhelha
person.givenNameLillian
person.givenNameRicardo C.
person.identifier469085
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id6507978333
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication2d5d1a41-7561-4a01-871c-b4c97da35053
relation.isAuthorOfPublication.latestForDiscovery2d5d1a41-7561-4a01-871c-b4c97da35053

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