Repository logo
 
Publication

Visualization of the cell-free layer (CFL) in a PDMS microchannel with a micro-stenosis

2013Book part Open access
Simple item page
dc.contributor.authorPinho, Diana
dc.contributor.authorYaginuma, Tomoko
dc.contributor.authorFaustino, Vera
dc.contributor.authorPinto, Elmano
dc.contributor.authorRodrigues, Raquel Oliveira
dc.contributor.authorCidre, Diana
dc.contributor.authorPereira, Ana I.
dc.contributor.authorLima, Rui A.
dc.date.accessioned2014-01-07T14:47:48Z
dc.date.available2014-01-07T14:47:48Z
dc.date.issued2013
dc.description.abstractRed blood cells (RBCs) have a tendency to undergo axial migration due to the parabolic velocity profile which results in a high shear stress around wall that forces the RBC to move towards the center induced by the tank treading motion of the RBC membrane. As a result there is a formation of cell-free layer (CFL) with extremely low concentration of cells. Based on this phenomenon several works have proposed microfluidic designs to separate the suspending physiological fluid from whole in vitro blood. However, most of these studies have the aim of the complete extraction of cells from plasma which is not the case of the present study. The biomedical device that is present in this work aims to obtain a CFL with a low enough RBC propose a combination of image analysis techniques able to measure automatically the CFL thickness before and after micro-stenosis is used.por
dc.identifier.citationPinho, D.; Yaginuma, T.; Faustino, V.; Pinto, E.; Rodrigues, R. O.; Cidre, D.; Pereira, Ana I.; Lima, R. (2013). Visualization of the cell-free layer (CFL) in a PDMS microchannel with a micro-stenosis. In Rubio-Hernández, F.J. [et al.](eds) Perspectives in Fundamental and Applied Rheology. p.363-367.ISBN 978-84-616-6551-8por
dc.identifier.isbn978-84-616-6551-8
dc.identifier.urihttp://hdl.handle.net/10198/9107
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherRubio-Hernández, F. J., et al.por
dc.relationANEURYSM - Hemodynamic Study in Cerebral Aneurysms
dc.relationHemo-Networks - Experimental and computational investigations of the factors influencing blood flow in microvascular networks.
dc.relationBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
dc.subjectCell free layerpor
dc.subjectPlasma layerpor
dc.titleVisualization of the cell-free layer (CFL) in a PDMS microchannel with a micro-stenosispor
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleANEURYSM - Hemodynamic Study in Cerebral Aneurysms
oaire.awardTitleHemo-Networks - Experimental and computational investigations of the factors influencing blood flow in microvascular networks.
oaire.awardTitleBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FEME-MFE%2F099109%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-BEB%2F108728%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-ENB%2F116929%2F2010/PT
oaire.citation.endPage367por
oaire.citation.startPage363por
oaire.citation.titlePerspectives in Fundamental and Applied Rheologypor
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
person.familyNamePinho
person.familyNamePereira
person.familyNameLima
person.givenNameDiana
person.givenNameAna I.
person.givenNameRui A.
person.identifier.ciencia-id5214-ED0C-35E8
person.identifier.ciencia-id0716-B7C2-93E4
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0002-3884-6496
person.identifier.orcid0000-0003-3803-2043
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridF-3168-2010
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id15071961600
person.identifier.scopus-author-id18437397800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typebookPartpor
relation.isAuthorOfPublication02bf2dd9-33ed-4d87-b61d-ca39c51f8451
relation.isAuthorOfPublicatione9981d62-2a2b-4fef-b75e-c2a14b0e7846
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication.latestForDiscoverye9981d62-2a2b-4fef-b75e-c2a14b0e7846
relation.isProjectOfPublicationadd108a5-17d2-41ea-8731-e51fe8723bfe
relation.isProjectOfPublication34870e5f-cd6e-443b-91f6-12f1a7a74013
relation.isProjectOfPublication0785b517-d2cf-4d92-b2e1-d45afee17273
relation.isProjectOfPublication.latestForDiscovery34870e5f-cd6e-443b-91f6-12f1a7a74013

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
PFAppliedRheologyVisualizationCFL.pdf
Size:
321.16 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESTiG - Capítulos de Livros