Oral Contraceptive pill and psychoaffective effects

Coelho, André; Folga, Marta; Sousa, Simão; Nascimento, Luís; Taboada Costa, Xavier

Publication

Oral Contraceptive pill and psychoaffective effects

2025-10Conference object

datacite.subject.fos	Ciências Médicas
datacite.subject.sdg	03:Saúde de Qualidade
dc.contributor.author	Coelho, André
dc.contributor.author	Folga, Marta
dc.contributor.author	Sousa, Simão
dc.contributor.author	Nascimento, Luís
dc.contributor.author	Taboada Costa, Xavier
dc.date.accessioned	2025-10-31T16:45:02Z
dc.date.available	2025-10-31T16:45:02Z
dc.date.issued	2025-10
dc.description.abstract	Background: Oral contraceptive pills (OCP’s) are widely used for fertility control, yet their potential psychoaffective impact is increasingly debated in clinical research (1). Studies show that users may experience increased negative effects and reduced emotional well-being compared to non-users (2). Experimental data further suggest that hormonal contraception can significantly lower general well-being in healthy women (3). Objective: To assess how the use of OCPs and age are associated with the expression of positive and negative psychoaffective effects. Methodology: A cross-sectional, observational, and descriptive-correlational study with a quantitative approach. The non-probabilistic convenience sample included 291 women (aged 18-44) residing in Northern Portugal. Data were collected through an online questionnaire, which included the scale Positive and Negative Affect Schedule (PANAS-SF). Considering the type of variables, statistical analyses included the Kolmogorov-Smirnov, t-student, and ANOVA tests (p ⩽ 0.05). Results: OCP users reported lower levels of positive affect (M=28.40; SD=8.83) compared to non-users (M=34.51; SD=9.07; p⩽ 0.001). Regarding negative affect, users showed higher levels (M=25.31; SD=10.42) than non-users (M=19.96; SD=7.55; p⩽ 0.001). No significant differences were observed between the age groups (p > 0.05). Conclusion: The findings suggest an association between OCP use and a less favourable emotional profile, regardless of age. This raises critical ethical and clinical concerns about the underestimation of the psycho-subjective effects of oral contraception. In this context, it would be pertinent to consider measures such as periodic psychological follow-up, regular emotional screening, and informative sessions involving mental health professionals.	por
dc.identifier.citation	Coelho, André; Folga, Marta; Soua, Simão; nascimento, Luís; Taboada Costa, Xavier (2025). Oral Contraceptive pill and psychoaffective effects. In 13th APLF Annual Conference. Aveiro. ISSN 2042-0984. 16:5, p. 19-19
dc.identifier.doi	10.1177/ 20420986251379201
dc.identifier.issn	2042-0996
dc.identifier.issn	2042-0984
dc.identifier.uri	http://hdl.handle.net/10198/34910
dc.language.iso	eng
dc.peerreviewed	yes
dc.publisher	Associação Portuguesa de Licenciados em Farmácia (APLF)
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/
dc.subject	Psychoaffective effects
dc.subject	Oral contraceptive pill
dc.subject	Panas sacale
dc.title	Oral Contraceptive pill and psychoaffective effects	eng
dc.type	conference object
dspace.entity.type	Publication
oaire.citation.conferencePlace	Expo-Aveiro, Parque das Exposições
oaire.citation.endPage	19
oaire.citation.issue	5–71
oaire.citation.startPage	19
oaire.citation.title	13th APLF Annual Conference
oaire.citation.volume	16
oaire.version	http://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyName	Nascimento
person.familyName	Taboada Costa
person.givenName	Luís
person.givenName	Xavier
person.identifier.ciencia-id	9918-ED25-623E
person.identifier.ciencia-id	FF14-5C05-5276
person.identifier.orcid	0000-0002-1302-2570
person.identifier.orcid	0000-0002-5813-1228
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