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Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice

dc.contributor.authorFernandes, Filipa Alexandra
dc.contributor.authorOliveira, Paula A.
dc.contributor.authorPinto, M.L.
dc.contributor.authorVenâncio, Carlos
dc.contributor.authorFélix, Luís
dc.contributor.authorMedeiros-Fonseca, Beatriz
dc.contributor.authorCorreia, Rossana
dc.contributor.authorPrieto Lage, Miguel A.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorHeleno, Sandrina A.
dc.date.accessioned2024-12-20T16:30:04Z
dc.date.available2024-12-20T16:30:04Z
dc.date.issued2024
dc.description.abstractThis work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second experimental protocol, Group 3 consumed water and Group 4 consumed plant-based beverage for a limited time (4 h). Two experimental protocols were conducted to assess whether the exposure time to the beverage affects the animals’ physiological parameters, to determine if there is a possible daily limit for consumption of the product and to analyze their adverse effects. The mice consuming a beverage ingested a larger amount of drink and a smaller amount of food. Histologically there are no pathological changes in collected organs. The consumption of a plant-based beverage has been shown to have a positive effect on oxidative markers and can have a diuretic action. According to results, no behavioral changes or clinical signs of disease were observed throughout both experimental protocols, and no mortality was recorded.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (10.54499/UIDB/00690/2020 and 10.54499/UIDP/00690/2020), SusTEC (10.54499/LA/P/0007/2020) and CITAB (UID/04033/2020; https://doi.org/10.54499/UIDB/040 33/2020). National funding by FCT, through the individual research grant (10.54499/SFRH/BD/145467/2019) of Filipa Fernandes, and through the institutional scientific employment program-contract with Sandrina A. Heleno and Lillian Barros. To the MICINN for the contract to researcher Miguel A. Prieto.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFernandes, Filipa A.; Oliveira, Paula A.; Pinto, Maria L.; Venâncio, Carlos; Félix, Luis; Medeiros-Fonseca, Beatriz; Correia, Rossana; Prieto, Miguel A.; Ferreira, Isabel C.F.R.; Barros, Lillian; Heleno, Sandrina A. (2024). Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice. Food and Chemical Toxicology. ISSN 0278-6915. 194, p. 1-10pt_PT
dc.identifier.doi10.1016/j.fct.2024.115082pt_PT
dc.identifier.issn0278-6915
dc.identifier.urihttp://hdl.handle.net/10198/30770
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationMountain Research Center
dc.relationMountain Research Center
dc.relationAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
dc.relationCentre for the Research and Technology of Agro-Environmental and Biological Sciences
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectPlant-based beveragept_PT
dc.subjectCyperus esculentus L.pt_PT
dc.subjectIn vivo safety assessmentpt_PT
dc.subjectFVB/Npt_PT
dc.titleEffects of a Cyperus esculentus L. plant-based beverage on FVB/n female micept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/00690/2020
oaire.awardNumberUIDP/00690/2020
oaire.awardNumberLA/P/0007/2020
oaire.awardNumberUIDB/04033/2020
oaire.awardNumberSFRH/BD/145467/2019
oaire.awardTitleMountain Research Center
oaire.awardTitleMountain Research Center
oaire.awardTitleAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
oaire.awardTitleCentre for the Research and Technology of Agro-Environmental and Biological Sciences
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0007%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04033%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F145467%2F2019/PT
oaire.citation.endPage10pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleFood and Chemical Toxicologypt_PT
oaire.citation.volume194pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
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person.familyNamePrieto Lage
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person.familyNameHeleno
person.givenNameFilipa Alexandra
person.givenNameMiguel A.
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.givenNameSandrina A.
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person.identifier.ciencia-id8B18-3095-6FC9
person.identifier.orcid0000-0001-6807-1137
person.identifier.orcid0000-0002-3513-0054
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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