Publication
Epoxidation of 2-Styrylchromone derivatives
| dc.contributor.author | Santos, Clementina M.M. | |
| dc.contributor.author | Silva, Artur | |
| dc.contributor.author | Cavaleiro, José | |
| dc.contributor.author | Patonay, Támas | |
| dc.contributor.author | Lévai, Albert | |
| dc.date.accessioned | 2011-02-22T21:04:06Z | |
| dc.date.available | 2011-02-22T21:04:06Z | |
| dc.date.issued | 2004 | |
| dc.description.abstract | 2-Styrylchromones constitute a small group of natural heterocyclic compounds with significant biological properties. Certain natural and synthetic hydroxyl derivatives have shown important pharmacological and mainly antioxidant activities [1 ,2]. We are interested in the design of new 2-styrylchromones analogues containing hydroxyl groups at C-3 and in the Ca=C~ systems because they could increase the antioxidation activity of these type of compounds [2]. Our first approach is the preparation of epoxy systems and then we will try to open the epoxy ring to give the desired hydroxyl derivatives. We studied the epoxidation of 2-styryl-chromones 1 with hydrogen peroxide and iodosylbenzene using [salen Mn(lll)] as catalyst, and the epoxy products 2 were obtained in moderate yields. Since the best results were obtained with iodosylbenzene, we applied oxidant to compounds 3 in order to prepare 4. In this communication, we will report the synthetic details and the structural characterisation of the epoxides 3 and 4. | |
| dc.identifier.citation | Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José; Patonay, Támas; Levaí, Albert (2004). Epoxidation of 2-Styrylchromone Derivatives. In XXIst European Colloquim on Heterocyclic Chemistry. Sopron | por |
| dc.identifier.uri | http://hdl.handle.net/10198/3493 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.relation | Study of the reactivity and transformations of styrylchromones and related compounds | |
| dc.title | Epoxidation of 2-Styrylchromone derivatives | por |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Study of the reactivity and transformations of styrylchromones and related compounds | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/POCI/POCTI%2FQUI%2F38394%2F2001/PT | |
| oaire.citation.conferencePlace | Sopron, Hungria | por |
| oaire.citation.title | XXIst European Colloquim on Heterocyclic Chemistry | por |
| oaire.fundingStream | POCI | |
| person.familyName | Santos | |
| person.givenName | Clementina M.M. | |
| person.identifier.ciencia-id | 9018-DB9C-C590 | |
| person.identifier.orcid | 0000-0003-4380-7990 | |
| person.identifier.scopus-author-id | 7201458663 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | por |
| rcaap.type | conferenceObject | por |
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