Logo do repositório
 
Publicação

Phenolic composition and biological properties of cynara cardunculus l. Var. altilis petioles: Influence of the maturity stage

2021Artigo científico Acesso aberto
Ver registo simples
dc.contributor.authorMandim, Filipa
dc.contributor.authorPetropoulos, Spyridon Α.
dc.contributor.authorDias, Maria Inês
dc.contributor.authorPinela, José
dc.contributor.authorKostić, Marina
dc.contributor.authorSoković, Marina
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2021-12-06T10:30:20Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2021-12-06T10:30:20Z
dc.date.issued2021
dc.description.abstractHydroethanolic extracts of cardoon petioles collected at sixteen growth stages (P1–P16) were characterized in terms of their phenolic composition and bioactive potential (antioxidant, cytotoxic, anti-inflammatory, and antimicrobial activities). Fifteen phenolic compounds were tentatively identified (i.e., ten phenolic acids and five flavonoid glycosides); the main compounds were 5-O-caffeoylquinic and 1,5-di-O-caffeoylquinic acids. Samples collected at early maturity (P1–P4) presented a weak positive correlation between the higher content in polyphenols (P3: 101-mg/g extract) and better inhibition capacity against thiobarbituric acid reactive substance formation (TBARS; P3: IC50 = 5.0 µg/mL). Samples at intermediate maturation stages (P9) presented higher cytotoxic and anti-inflammatory potential. Moreover, immature petioles showed greater antihemolytic (OxHLIA; P4: IC50 = 65 and 180 µg/mL for Δt of 60 and 120 min, respectively) and antibacterial activity. The antifungal activity varied depending on the maturation stage and the fungi strain. In conclusion, the maturation stage may greatly affect the polyphenols composition and content and the bioactive potential of cardoon petioles.en_EN
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT; Portugal) for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020), for the F. Mandim PhD grant (SFRH/BD/146614/2019), and the J. Pinela (CEECIND/01001/2018) and M.I. Dias and L. Barros contracts through individual and institutional scientific employment program contracts. The authors are also grateful to the project TRANSCoLAB (0612_TRANS_CO_LAB_2_P), to the European Regional Development Fund (ERDF) through the Regional Operational Program North 2020, within the scope of Project GreenHealth, Norte-01-0145-FEDER-000042, and to the Ministry of Education, Science and Technological Development of the Republic of Serbia (451-03-68/2020-14/200007). GIPUSAL was funded by Junta de Castilla y León (Spain) through Project SA093P20 and the Strategic Research Program for Units of Excellence (ref. CLU-2018-04).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationMandim, Filipa; Petropoulos, Spyridon A.; Dias, Maria Inês; Pinela, José; Kostić, Marina; Soković, Marina; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.; Barros, Lillian (2021). Phenolic composition and biological properties of cynara cardunculus l. Var. altilis petioles: Influence of the maturity stage. Antioxidants. ISSN 2076-3921. 10:12, p. 1-19en_EN
dc.identifier.doi10.3390/antiox10121907en_EN
dc.identifier.issn2076-3921
dc.identifier.urihttp://hdl.handle.net/10198/24452
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationCEECIND/01001/2018
dc.relationMountain Research Center
dc.relationIntegrated strategies for the development of a novel functional beverage with sustainable production systems
dc.subjectAnti-inflammatory activityen_EN
dc.subjectAntimicrobial propertiesen_EN
dc.subjectAntioxidant activityen_EN
dc.subjectCardoonen_EN
dc.subjectOxidative hemolysisen_EN
dc.subjectPhenolic compositionen_EN
dc.subjectSeasonal changesen_EN
dc.titlePhenolic composition and biological properties of cynara cardunculus l. Var. altilis petioles: Influence of the maturity stageen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/00690/2020
oaire.awardNumberSFRH/BD/146614/2019
oaire.awardTitleMountain Research Center
oaire.awardTitleIntegrated strategies for the development of a novel functional beverage with sustainable production systems
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F146614%2F2019/PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMandim
person.familyNameDias
person.familyNamePinela
person.familyNameFerreira
person.familyNameBarros
person.givenNameFilipa
person.givenNameMaria Inês
person.givenNameJosé
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.identifier144781
person.identifier469085
person.identifier.ciencia-idF318-9049-EB99
person.identifier.ciencia-id2A13-4BE6-C7CF
person.identifier.ciencia-id771C-2B43-B108
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0002-6494-2326
person.identifier.orcid0000-0001-8744-7814
person.identifier.orcid0000-0001-7523-1637
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridM-8242-2013
person.identifier.ridB-4466-2014
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54388787000
person.identifier.scopus-author-id54392272800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublicationbcc274d4-7e6c-46a8-8e49-2752f9dbfbcd
relation.isAuthorOfPublication7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isAuthorOfPublication706cd9ff-065b-4c98-98a7-5c0a9e45adc4
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isProjectOfPublication29718e93-4989-42bb-bcbc-4daff3870b25
relation.isProjectOfPublication6f42bb4f-993a-4998-afc5-030cd08f965b
relation.isProjectOfPublication.latestForDiscovery6f42bb4f-993a-4998-afc5-030cd08f965b

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
1.pdf
Tamanho:
2.17 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.75 KB
Formato:
Plain Text
Descrição:
Ver/Abrir

Coleções

CIMO - Artigos em Revistas Indexados à WoS/Scopus