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Cistus ladanifer as a source of phenolic compounds with antifungal activity

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dc.contributor.authorBarros, Lillian
dc.contributor.authorDueñas, Montserrat
dc.contributor.authorAlves, Carlos Tiago
dc.contributor.authorSilva, Sónia
dc.contributor.authorHenriques, Mariana
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2013-01-03T18:24:30Z
dc.date.available2013-01-03T18:24:30Z
dc.date.issued2012
dc.description.abstractA screening of the antifungal potential of phenolic extract of Cistus ladanifer from Northeast Portugal, against Candida species was performed. The extract was characterized by HPLC-DAD-ESI/MS. Phenolic acids and derivatives, ellagic acid derivatives and flavonoids, such as catechins, flavonols and flavones, were found in the sample. The most abundant group was ellagic acid derivatives in which punicalagin gallate, a derivative of punicalagin attached to gallic acid, was found in highest amount. These compounds could be related to the strong inhibition of C. albicans, C. glabrata and C. parapsilosis growth. Moreover, the best antifungal activity was against C. glabrata, where the studied extract was able to cause at least 3 Log of reduction at concentrations below 50 µg/mL and a total growth inhibition at concentrations above 625 µg/mL.por
dc.identifier.citationBarros, Lillian; Dueñas, Montserrat; Alves, Carlos Tiago; Silva, Sónia; Henriques, Mariana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2012). Cistus ladanifer as a source of phenolic compounds with antifungal activity. In International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF. New York e Planta Medica-. ISSN 0032-0943. 78:11, p. 1126por
dc.identifier.urihttp://hdl.handle.net/10198/7810
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationStrategic Project - UI 690 - 2011-2012
dc.relationEMBEDDED SYSTEMS FOR ELLIPTIC CURVE
dc.titleCistus ladanifer as a source of phenolic compounds with antifungal activitypor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardTitleEMBEDDED SYSTEMS FOR ELLIPTIC CURVE
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/PIDDAC/SFRH%2FBD%2F44609%2F2008/PT
oaire.citation.conferencePlaceNew York city, USApor
oaire.citation.startPage1126por
oaire.citation.titlePlanta Medica; 8th Joint Meeting of AFERP, ASP, GA, PSE & SIF, 28th July-1st August 2012por
oaire.citation.volume78por
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPIDDAC
person.familyNameBarros
person.familyNameFerreira
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8
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