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Cell-free layer measurements in a network with bifurcating microchannels using a global approach

dc.contributor.authorBento, David
dc.contributor.authorPinho, Diana
dc.contributor.authorPereira, Ana I.
dc.contributor.authorLima, Rui A.
dc.date.accessioned2018-04-23T13:24:42Z
dc.date.available2018-04-23T13:24:42Z
dc.date.issued2015
dc.description.abstractOne of the most interesting hemodynamic phenomenon observed in microchannels is the existence of a marginal cell-free layer (CFL) at regions adjacent to the wall. This is a well known phenomenon that occurs in simple glass capillaries and in vivo microvessels, but has never been investigated in detail in biomedical microdevices containing complex geometries. In the present chapter, in vitro blood flowing through bifurcating microchannels was studied, with the aim of characterizing the cell-free layer (CFL). For that three different videos with different hematocrit and flow rates were considered. All images were obtained by means of a high-speed video microscopy system and then processed in MatLab using the Image Processing toolbox. The numerical data was obtained automatically and analyzed by optimization techniques using the genetic algorithm approach. The results suggest that the CFL were formed in a similar way at the upper and lower regions in all bifurcations.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBento, David; Pinho, Diana; Pereira, Ana I.; Lima, R. (2015). Cell-free layer measurements in a network with bifurcating microchannels using a global approach. IIn Almeida, João Paulo; Oliveira, José F.; Pinto, Alberto A. (Eds.) Operational Research e 16th National Conference of the APDIO. p. 53-65. ISBN 978-3-319-20328-7pt_PT
dc.identifier.doi10.1007/978-3-319-20328-7_4pt_PT
dc.identifier.isbn978-3-319-20328-7
dc.identifier.urihttp://hdl.handle.net/10198/17170
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectOptimizationpt_PT
dc.subjectCell-free layerpt_PT
dc.titleCell-free layer measurements in a network with bifurcating microchannels using a global approachpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPage65pt_PT
oaire.citation.startPage53pt_PT
oaire.citation.titleOperational Research. CIM Series in Mathematical Sciencespt_PT
oaire.citation.volume4pt_PT
person.familyNamePinho
person.familyNamePereira
person.familyNameLima
person.givenNameDiana
person.givenNameAna I.
person.givenNameRui A.
person.identifier.ciencia-id5214-ED0C-35E8
person.identifier.ciencia-id0716-B7C2-93E4
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0002-3884-6496
person.identifier.orcid0000-0003-3803-2043
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridF-3168-2010
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id15071961600
person.identifier.scopus-author-id18437397800
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication02bf2dd9-33ed-4d87-b61d-ca39c51f8451
relation.isAuthorOfPublicatione9981d62-2a2b-4fef-b75e-c2a14b0e7846
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication.latestForDiscovery02bf2dd9-33ed-4d87-b61d-ca39c51f8451

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