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A critical appraisal of the most recent investigations on the hepatoprotective action of brazilian plants

dc.contributor.authorGarcia-Manieria, Jéssica A.A.
dc.contributor.authorCorrea, Vanesa G.
dc.contributor.authorBackes, Emanueli
dc.contributor.authorSa-Nakanishi, Anacharis Babeto de
dc.contributor.authorBracht, Lívia
dc.contributor.authorComar, Jurandir Fernando
dc.contributor.authorCorrêa, Rúbia C.G.
dc.contributor.authorPeralta, Rosane M.
dc.contributor.authorBracht, Adelar
dc.date.accessioned2018-01-31T10:00:00Z
dc.date.accessioned2018-01-31T15:40:38Z
dc.date.available2018-01-31T10:00:00Z
dc.date.available2018-01-31T15:40:38Z
dc.date.issued2022
dc.description.abstractConventional treatments for liver diseases are often burdened by side effects caused by chemicals. For minimizing this problem, the search for medicines based on natural products has increased. The objective of this review was to collect data on the potential hepatoprotective activity of plants of the Brazilian native flora. Special attention was given to the modes of extraction, activity indicators, and identification of the active compounds. The databases were Science direct, Pubmed, and Google Academic. Inclusion criteria were: (a) plants native to Brazil; (b) studies carried out during the last 15 years; (c) high-quality research. A fair number of communications met these criteria. Various parts of plants can be used, e.g., fruit peels, seeds, stem barks, and leaves. An outstanding characteristic of the active extracts is that they were mostly obtained from plant parts with low commercial potential, i.e., by-products or bio-residues. The hepatoprotective activities are exerted by constituents such as flavonoids, phenolic acids, vitamin C, phytosterols, and fructose poly- and oligosaccharides. Several Brazilian plants present excellent perspectives for the obtainment of hepatoprotective formulations. Very important is the economical perspective for the rural producers which may eventually increase their revenue by selling increasingly valued raw materials which otherwise would be wasted.en_EN
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationGarcia-Manieria, Jéssica A.A.; Correa, Vanesa G.; Backes, Emanueli; Sa-Nakanishi, Anacharis Babeto de; Bracht, Lívia; Comar, Jurandir Fernando; Corrêa, Rúbia C.G.; Peralta, Rosane M.; Bracht, Adelar. (2022). A critical appraisal of the most recent investigations on the hepatoprotective action of brazilian plants. Plants. eISSN 2223-7747. 11:24, p. 1-21en_EN
dc.identifier.eissn2223-7747
dc.identifier.urihttp://hdl.handle.net/10198/15368
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.publisherMDPI
dc.subjectLiver damageen_EN
dc.subjectCo-productsen_EN
dc.subjectBioactive compoundsen_EN
dc.subjectAntioxidantsen_EN
dc.titleA critical appraisal of the most recent investigations on the hepatoprotective action of brazilian plantsen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titlePlants
person.familyNameBackes
person.familyNameCorrêa
person.givenNameEmanueli
person.givenNameRúbia C.G.
person.identifier.ciencia-id6C1F-2818-CBB5
person.identifier.orcid0000-0003-2875-9097
person.identifier.orcid0000-0003-0269-4344
person.identifier.scopus-author-id37661286600
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublication988677cd-0d4a-48fb-8f49-790710f55ca9
relation.isAuthorOfPublication35cf5f0f-d5bc-49ad-9704-e6613e60f0fc
relation.isAuthorOfPublication.latestForDiscovery35cf5f0f-d5bc-49ad-9704-e6613e60f0fc

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