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Phenolic constituents of lamium album: focus on isoscutellarein derivatives

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dc.contributor.authorPereira, Olívia R.
dc.contributor.authorDomingues, Maria R.M.
dc.contributor.authorSilva, Artur
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2012-09-24T13:03:26Z
dc.date.available2012-09-24T13:03:26Z
dc.date.issued2012
dc.description.abstractLamium album L. is an edible plant which is consumed raw or cooked, in particular in the Mediterranean and surrounding areas. It is also consumed as tea infusions and as a main component of food supplements, because of its pharmacological effects. Despite being consumed by humans for centuries, the chemical composition of L album L is far from being understood. In this study, a purified ethanolic extract (PEEL) was prepared and further analyzed by high performance liquid chromatography and electrospray mass spectrometry. Overall, verbascoside accounted for approximately half of the phenolic content of the extract, but this also contained other bioactive phenolic compounds herein detected for the first time in the genus, namely isoscutellarein derivatives. The latter included isoscutellarein-7-O-allosyl(1 -> 2)glucoside, its O-methyl derivative, three acetyl derivatives of isoscutellarein-O-allosyl glucoside and one acetylated form of O-methylisoscutellarein-7-O-allosyl(1 -> 2)glucoside. From those, the main isoscutellarein derivative was assigned to isoscutellarein-7-O-(6-O-acetyl-beta-allosyl)(1 -> 2)-beta-glucoside, as confirmed by NMR. Altogether, isoscutellarein derivatives accounted for almost 30% of PEEL phenolics. Since verbascoside and isoscutellarein derivatives are main components of L album L ethanolic extract, their possible association to the health benefits of the plant is discussed.por
dc.identifier.citationPereira, Olívia R.; Domingues, Maria R. M.; Silva, Artur M. S.; Cardoso, Susana M. (2012). Phenolic constituents of lamium album: focus on isoscutellarein derivatives. Elsevier . ISSN 0963-9969. 48:1, p. 330-335por
dc.identifier.doi10.1016/j.foodres.2012.04.009
dc.identifier.issn0963-9969
dc.identifier.urihttp://hdl.handle.net/10198/7587
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationREDE/1504/REM/2005
dc.relationStrategic Project - UI 681 - 2011-2012
dc.relationStrategic Project - UI 62 - 2011-2012
dc.subjectLamium albumpor
dc.subjectVerbascosidepor
dc.subjectIsoverbascosidepor
dc.subjectIsoscutellarein derivativespor
dc.subjectHigh performance liquid chromatographypor
dc.subjectElectrospray ionization-mass spectrometrypor
dc.titlePhenolic constituents of lamium album: focus on isoscutellarein derivativespor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 681 - 2011-2012
oaire.awardTitleStrategic Project - UI 62 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0681%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FQUI%2FUI0062%2F2011/PT
oaire.citation.conferencePlaceAMSTERDAM, NETHERLANDSpor
oaire.citation.endPage335por
oaire.citation.startPage330por
oaire.citation.titleFood Research Internationalpor
oaire.citation.volume48por
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6820 - DCRRNI ID
person.familyNamePereira
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453
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