Repository logo
 
Publication

Persistence of antioxidant properties of Carpobrotus edulis L. extract after in vitro digestion

2022Conference object Open access
Simple item page
dc.contributor.authorOliveira, Daniela
dc.contributor.authorDias, Maria Inês
dc.contributor.authorBarros, Lillian
dc.contributor.authorCustódio, Luísa
dc.contributor.authorOliveira, Rui
dc.date.accessioned2022-07-14T09:04:16Z
dc.date.available2022-07-14T09:04:16Z
dc.date.issued2022
dc.description.abstractThe human being is unknowingly cxposcd to many toxic chcrnicals through diet, which can trigger an excessive pra ductian a f reactive oxygen and ni trogen species that can cause a redax imbalance and generate oxidativc stress in thc gastrointcstin al tract, potcntially contri buting to the development of degenerative discases. In fact, oxidative stress has becn indi cated to contribute to ali three phases a f carcinogenesis. Thus, the attenuation of oxidative strcss could contribute to the prevention of cancer in itiation. Halophytes are associated wi th strong ant ioxidant capacity, which makes them excellent candidates to anen uale lhe oxidative stress in the gaslrointestinal tracl. For instance, Carpobrotus edulis L is an edible halophyte 1hal has been reported for its antioxidant properties and high content in phenolic compounds. However, most of these stud ies did not consider the impact of digeslion, which can alter the chemical structure of the phytochemicals and possibly their biaacti vilics. To our knowledge, there are no studies considering the efTect of digestion on lhe antiox idant properti es of C. edulis. The objecti ve of th is work was to evaluate the impact of digestion on the chemical compos ition and ant ioxidant capacity of C. edulis aerial part ethanol extract (CEE). The extract was subjected to in vilro simulation of human digestion (IVO) and aI the end we obtained the digesled extracl lhat becomes avai lable in lhe colon (DCEE). Both forms of lhe extract were subjected to chemical characterization by lhe Folin-Ciocalteu melhod and by LC-DADESI/ MS· to delect alterations caused by IVO. The anti oxidant capacity ofCEE and DCEE was evaluated in vi/ro by determ in ati an of scavenging of ni lric oxide (NO) and 2,2-diphenyl- l picrylhydrazyl (DPPH) rad icaIs and in viab il ity assays again st hydrogen peroxide (H,O,) in the yeast Saccharomyces cerevisiae. The resu lts showed Ihat lhe phenolic composition ofCEE was severely affected by IVO. as wel! as the capacity to scavenge the OPPH radical In oppositian, the capac ity to scavenge the NO rad ical increased. Moreover, CEE protected yeast cel ls against 1-1,0" corroborating the antioxidant propert ies reported in the li leralure. These properties seem to pers isl after IVO, bUl at a lower extent. Thus, although the IVD s ignificantly altered the chemi cal compos it ion of CEE and decreased the antioxidant capacity, lhe beneficiai effect is still relevant since it provided pratect ion against oxidative stress in the viabi lity assay in S. cerevisiae. Thercforc. C. edlllis scems to have potent ia l to be included in the human diet to decrease the oxidative stress generated in the gastrointestinal tract due to lhe recurrent consumption of contaminated foods and lhus could play a role in the prevention of carcinogenesis.pt_PT
dc.description.sponsorshipThis work was supported by national funds through FCT (PD/BD/135329/2017). under PHD AgriChains (PD/00122/2012) and from lhe European Social Funds and lhe Regional Operational programme Norte 2020. This study was also supported by CITAB (UIDB/04033/2020) and by CBMA ("Contrato-Programa" UIDB/04050/2020 funded by national funds through the FCT I.P.). The authors are grateful to FCT for financial support through national funds FCT/MCTESF to CIMO (UIDB/00690/2020). L. Custódio acknowledges FCT for lhe UIDB/04326/2020 and PTDC/BAA-AGR/1391/2020 projects and Scientific Employment Stimulus (CEECIND/00425/2017).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOliveira, Daniela; Dias, Maria Inês; Barros, Lillian; Custódio, Luísa; Oliveira, Rui (2022). Persistence of antioxidant properties of Carpobrotus edulis L. extract after in vitro digestion. In Fernanda Delgado; Joana Domingues (Eds.) III Colóquio Nacional de Plantas Aromáticas e Medicinais: livro de resumos. Castelo Brancopt_PT
dc.identifier.isbn978-972-8936-43-3
dc.identifier.urihttp://hdl.handle.net/10198/25642
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherInstituto Politécnico de Castelo Brancopt_PT
dc.relationPD/00122/20122020/PTpt_PT
dc.relationNot Available
dc.relationExploring salt tolerant plants as sources of innovative food additives
dc.relationAlgarve Centre for Marine Sciences
dc.relationMountain Research Center
dc.relationValorisation of halophyte plants present in Portuguese territory through the investigation of their protective effects against food toxicants - Study of bioactivities of plant-based products to attenuate the effects of food toxicants
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectOxidative stresspt_PT
dc.subjectBioactivitypt_PT
dc.subjectHalophytept_PT
dc.subjectSimulation of digestionpt_PT
dc.titlePersistence of antioxidant properties of Carpobrotus edulis L. extract after in vitro digestionpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleNot Available
oaire.awardTitleExploring salt tolerant plants as sources of innovative food additives
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleMountain Research Center
oaire.awardTitleValorisation of halophyte plants present in Portuguese territory through the investigation of their protective effects against food toxicants - Study of bioactivities of plant-based products to attenuate the effects of food toxicants
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 2017/CEECIND%2F00425%2F2017%2FCP1391%2FCT0001/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBAA-AGR%2F1391%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/PD%2FBD%2F135329%2F2017/PT
oaire.citation.conferencePlaceCastelo Brancopt_PT
oaire.citation.endPage51pt_PT
oaire.citation.startPage50pt_PT
oaire.citation.titleIII Colóquio Nacional de Plantas Aromáticas e Medicinaispt_PT
oaire.fundingStreamCEEC IND 2017
oaire.fundingStream3599-PPCDT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
person.familyNameDias
person.familyNameBarros
person.familyNameOliveira
person.givenNameMaria Inês
person.givenNameLillian
person.givenNameRui
person.identifier469085
person.identifier.ciencia-id2A13-4BE6-C7CF
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idBE1A-620F-6670
person.identifier.orcid0000-0001-8744-7814
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4444-2591
person.identifier.ridM-8242-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54388787000
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id57193743231
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication18758fbc-c57f-48fb-bcec-25f449279fd5
relation.isAuthorOfPublication.latestForDiscovery7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isProjectOfPublicationf94b1b33-3fbc-4e57-a997-3efb951f68a3
relation.isProjectOfPublicationefc3f1d8-4659-4779-bcdb-53de0c967896
relation.isProjectOfPublication7eaadfa0-30a0-462b-b852-84f780097a7d
relation.isProjectOfPublication29718e93-4989-42bb-bcbc-4daff3870b25
relation.isProjectOfPublication9203a8e7-00f8-450e-8285-c4d070db316a
relation.isProjectOfPublication.latestForDiscoveryefc3f1d8-4659-4779-bcdb-53de0c967896

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
El - [1].OralNacional_MInêsDias.pdf
Size:
1.27 MB
Format:
Adobe Portable Document Format
Download

Collections

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus