Publication
Bioactive properties of the endemic algerian Myrtus nivelii Batt & Trab.: scientific approaches to the traditional uses
| dc.contributor.author | Rached, Wahiba | |
| dc.contributor.author | Bennaceur, Malika | |
| dc.contributor.author | Barros, Lillian | |
| dc.contributor.author | Calhelha, Ricardo C. | |
| dc.contributor.author | Heleno, Sandrina A. | |
| dc.contributor.author | Alves, Maria José | |
| dc.contributor.author | Carvalho, Ana Maria | |
| dc.contributor.author | Marouf, Abderrazak | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.date.accessioned | 2019-01-31T15:49:30Z | |
| dc.date.available | 2019-01-31T15:49:30Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Myrtus nivelli ileaves are widely used in the Algerian folk medicine, due toits healthpromoting properties attributed to the phenolic composition. In this context, bioactivities of the aqueous extract and its organic sub-fractions (ethyl acetate and butanol) were evaluated with focus onantioxidant properties (free radicals’ scavenging activity, reducing power, inhibition of β-carotene blanching andlipid peroxidation), anti-inflammatory potential. (inhibition of NO production in lipopolysaccharide-stimulated RAW 264.7 macrophages), cytotoxicity for human tumor cells and normal porcine liver primary cells, and antibacterial activity against ten clinical isolates. The obtained results indicated high activities for all the tested samples. The antioxidant activity was higher than that obtained for Trolox (positive control), showing the ethylacetate fraction the highest activity as also the highest inhibition of NO production (EC50= 104 ± 6 μg/mL) and cytotoxicity for all the tested tumor cell lines (HeLa- 15.39±1 μg/mL, MCF-7- 16.12± 1μg/mL, NCI-H460-, HepG2-17.67±1 μg/mL and 49.01 ± 3 μg/mL). The butanol fraction and the crude aqueous extract presented the highest antibacterial activity. Overall, this study highlights the potential of M. nivellii leaves in the preparation of bioactive ingredients. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10198/18604 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Myrtus nivellii | pt_PT |
| dc.subject | Extract/fractions | pt_PT |
| dc.subject | Antioxidant | pt_PT |
| dc.subject | Anti-inflammatory | pt_PT |
| dc.subject | Cytotoxicity | pt_PT |
| dc.subject | Antibacterial | pt_PT |
| dc.title | Bioactive properties of the endemic algerian Myrtus nivelii Batt & Trab.: scientific approaches to the traditional uses | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Jahorina, Bósnia | pt_PT |
| oaire.citation.title | IX International Scientific Agriculture Symposium “AGROSYM 2018” | pt_PT |
| person.familyName | Barros | |
| person.familyName | Calhelha | |
| person.familyName | Heleno | |
| person.familyName | Alves | |
| person.familyName | Carvalho | |
| person.familyName | Ferreira | |
| person.givenName | Lillian | |
| person.givenName | Ricardo C. | |
| person.givenName | Sandrina A. | |
| person.givenName | Maria José | |
| person.givenName | Ana Maria | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 469085 | |
| person.identifier | ID G-7399-2011 | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 9616-35CB-D001 | |
| person.identifier.ciencia-id | F313-E3CE-554E | |
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| person.identifier.ciencia-id | D31A-35AF-E2A9 | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0002-9050-5189 | |
| person.identifier.orcid | 0000-0002-6801-4578 | |
| person.identifier.orcid | 0000-0001-7224-1098 | |
| person.identifier.orcid | 0000-0001-8506-4393 | |
| person.identifier.orcid | 0000-0001-5508-5935 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | J-3600-2013 | |
| person.identifier.rid | J-2172-2014 | |
| person.identifier.rid | L-5951-2014 | |
| person.identifier.rid | M-6624-2016 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 35236343600 | |
| person.identifier.scopus-author-id | 6507978333 | |
| person.identifier.scopus-author-id | 30067731800 | |
| person.identifier.scopus-author-id | 16400584800 | |
| person.identifier.scopus-author-id | 20336503900 | |
| person.identifier.scopus-author-id | 36868826600 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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