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Advisor(s)
Abstract(s)
Disruption of the balance between reactive oxygen species (ROS) production and elimination leads to oxidative stress. As a consequence, ROS are known to be implicated in many cell disorders and in the development of many diseases including cardiovascular diseases, cancer, atherosclerosis, cataracts, chronic inflammation, or neurodegenerative diseases' To find new natural sources 01 bioactive compounds, the antioxidant properties 01 almond green barks, chestnut skins (inner and outer) and chestnut leaves, were evaluated through several chemical and biochemical assays: DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging acclivity, reducing power, inhibition 01 i3-carolene
bleaching, inhibition 01 oxidative hemolysis in erythrocytes, induced by 2,2'-azobis(2- amidinopropane)di-hydrochloride (AAPH), and inhibition of lipid peroxidation in pig brain tissue
through formation of thiobarbituric acid reactive substances (TBARS).
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Citation
Barreira, João C.M.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P.P.; Pereira, José Alberto (2008). Almond and chestnut by-products as new natural sources of healthy bioactive compounds. In International Conference in Medicinal Chemistry: Interfacing Chemical Biology, Natural Products and Drug Discovery. Angers