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Advisor(s)
Abstract(s)
O despiste de ferropenia pré operatório numa população pediátrica, pode constituir uma oportunidade para detectar e corrigir estadios deficitários de ferro, susceptíveis de provocar sequelas a médio/longo prazo. Com o objectivo de detectar estas situações, fomos avaliar sistematicamente em todos os hemogramas, que deram entrada no Serviço
de Patologia Clínica do Hospital Maria Pia num período de 6 meses, a presença de indicadores de défice de ferro,
nomeadamente: hemoglobina (Hb), volume globular médio e RDW (red cell distribution width). Nos casos em que foi encontrada alteração em algum destes parâmetros foi
efectuado: protoporfirina eritrocitária livre (PEL), ferro, ferritina e transferrina. Nas situações que confirmaram a
presença de microcitose sem défice de ferro foi efectuado o doseamento de Hb A2 e Hb F e pesquisa de inclusões de Hb H. Das 557 amostras que deram entrada para estudo
de rotina pré-operatória, nove (1,62%) apresentaram alteração de pelo menos um dos parâmetros considerados para despiste de ferropenia. Sete destas amostras revelaram
ferropenia, duas das quais associadas a anemia e as outras duas apresentavam a pesquisa de inclusões de Hb H positivas, sugestivo do diagnóstico de α-talassemia minor.
Com o presente trabalho pensamos ter contribuído, a diferentes níveis, para o aproveitamento integral de todas as
informações analíticas fornecida pelos modernos contadores hematológicos.
Preoperative haematological evaluation could be an opportunity to detect and correct iron deficiency in paediatric population. With this objective we screened this deficiency in a six-month period, searching for alterations in haemoglobin (Hb), median globular volume and/or red cell distribution width. In cases in which no alterations were found additional laboratory test were performed, namely: zinc protoporphyrin, iron, ferritin and transferrin. Situations associated with microcytosis without iron deficiency, HbA2, HbF and HbH inclusions were performed. In a six month period, 557 blood samples were studied. Nine of them (1,62%) presented an alteration in at least one parameter. Seven were associated with iron deficiency, from which two of them were associated with anaemia. The other two cases were positive for the presence of HbH inclusions, suggesting the α-thalassaemia minor diagnosis. With the present work we think to have contributed, at different levels, for the integral exploitation of all the analytical information supplied by the modern haematological counters.
Preoperative haematological evaluation could be an opportunity to detect and correct iron deficiency in paediatric population. With this objective we screened this deficiency in a six-month period, searching for alterations in haemoglobin (Hb), median globular volume and/or red cell distribution width. In cases in which no alterations were found additional laboratory test were performed, namely: zinc protoporphyrin, iron, ferritin and transferrin. Situations associated with microcytosis without iron deficiency, HbA2, HbF and HbH inclusions were performed. In a six month period, 557 blood samples were studied. Nine of them (1,62%) presented an alteration in at least one parameter. Seven were associated with iron deficiency, from which two of them were associated with anaemia. The other two cases were positive for the presence of HbH inclusions, suggesting the α-thalassaemia minor diagnosis. With the present work we think to have contributed, at different levels, for the integral exploitation of all the analytical information supplied by the modern haematological counters.
Description
Keywords
Ferropenia Crianças Pré-operatório Pediatria α-Talassemia minor
Citation
Bioanálise. ISSN 1646-1266. 3:2 (2006) 86-93
Publisher
Sociedade Portuguesa de Bioanalistas da Saúde