Publication
Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius
| dc.contributor.author | Afonso, Andrea Luísa Fernandes | |
| dc.contributor.author | Pereira, Olívia R. | |
| dc.contributor.author | Silva, Artur | |
| dc.contributor.author | Cardoso, Susana M. | |
| dc.date.accessioned | 2018-09-13T09:56:47Z | |
| dc.date.available | 2018-09-13T09:56:47Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | The genus Thymus, belonging to Lamiaceae family, is rich in medicinal and aromatic species and well-known by several health promoting activities [1,2]. Despite this genus has been extensively studied, some species remain unexploited. In this study, Thymus herba-barona, Thymus pseudolanuginosus and Thymus caespititius decoctions were screened for their phenolic constituents by ultra-high performance liquid chromatography coupled to diode array detector and an electrospray mass spectrometer (UHPLC-DAD-ESI-MSn) operating in negative mode. The three aqueous extracts were rich in caffeic acid derivatives, mainly rosmarinic acid (MW 359) and its structural isomers, that accounted for 55.8 ± 2.8 mg/g in T. herba-barona and 40.2 ± 0.9 and 43.2 ± 3.2 mg/g in T. pseudolanuginosus and T. caespititius, respectively. In turn, other depsides were differently distributed in the three Thyme extracts: while dihydro-salvianolic acid B (MW 716 Da) and caffeoyl rosmarinic acid were particularly representative in T. herba-barona, salvianolic acids K ([M-H]− at m/z 555 493 359) and B ( [M-H]− at m/z 717 519 475) were found in moderate amounts in T. caespititius extract. On the other hand, T. pseudolanuginosus was clearly distinguished by its richness in the flavone luteolin-O-glucuronide ([M − H]− at m/z 461→285). Overall, this work is an important contribution for the phytochemical characterization of these three Thymus species, which are poorly explored. | pt_PT |
| dc.description.sponsorship | Thanks are due to University of Aveiro, FCT/MEC for the financial support to the QOPNA research Unit (FCT UID/QUI/00062/2013) and CIMO (UID/AGR/00690/2013), through national funds and where applicable co-financed by the FEDER, within the PT2020 Partnership Agreement. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Afonso, Andrea F.; Pereira, Olívia R.; Silva, Artur M.S.; Cardoso, Susana M. (2017). Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. Caespititius. In 10º Encontro Nacional de Cromatografia. Bragança: Instituto Politécnico | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10198/17959 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Instituto Politécnico de Bragança | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Thymus | pt_PT |
| dc.subject | Chemical characterization | pt_PT |
| dc.subject | T. herba-barona | pt_PT |
| dc.subject | T. pseudolanuginosus | pt_PT |
| dc.subject | T. caespititius | pt_PT |
| dc.title | Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT | |
| oaire.citation.conferencePlace | Bragança | pt_PT |
| oaire.citation.title | 10º Encontro Nacional de Cromatografia | pt_PT |
| oaire.fundingStream | 5876 | |
| person.familyName | Afonso | |
| person.familyName | Pereira | |
| person.givenName | Andrea Luísa Fernandes | |
| person.givenName | Olívia R. | |
| person.identifier | 145216 | |
| person.identifier.ciencia-id | 9C1D-41E7-9BBF | |
| person.identifier.ciencia-id | B312-AF21-D2FA | |
| person.identifier.orcid | 0000-0002-8858-1617 | |
| person.identifier.orcid | 0000-0002-6275-3134 | |
| person.identifier.rid | H-1049-2014 | |
| person.identifier.scopus-author-id | 36766901000 | |
| person.identifier.scopus-author-id | 52264387000 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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