Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane

Patoilo, Diana; Silva, Artur; Pinto, Diana; Santos, Clementina M.M.; Tomé, Augusto; Cavaleiro, José

Publication

Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane

2012Journal article

dc.contributor.author	Patoilo, Diana
dc.contributor.author	Silva, Artur
dc.contributor.author	Pinto, Diana
dc.contributor.author	Santos, Clementina M.M.
dc.contributor.author	Tomé, Augusto
dc.contributor.author	Cavaleiro, José
dc.date.accessioned	2013-03-15T16:27:10Z
dc.date.available	2013-03-15T16:27:10Z
dc.date.issued	2012
dc.description.abstract	The Diels-Alder reaction of (E)-2-styrylchromones with a pyrimidine ortho-quinodimethane is reported for the first time. These cycloaddition reactions afford mixtures of two regioisomeric tetrahydroquinazoline-substituted chromones in moderate to excellent global yields. Irrespectively of the substituents on the 2-styrylchromones, the 2-(7-aryl-4-methoxy-2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)chromone derivatives are always the major isomers.	por
dc.identifier.doi	10.1016/j.tetlet.2012.03.081
dc.identifier.issn	0040-4039
dc.identifier.uri	http://hdl.handle.net/10198/8274
dc.language.iso	eng	por
dc.peerreviewed	yes	por
dc.publisher	Elsevier	por
dc.subject	Tetrahydroquinazolines	por
dc.subject	Cycloadditions	por
dc.subject	2-Styrylchromones	por
dc.subject	Pyrimidine ortho-Quinodimethane	por
dc.subject	NMR	por
dc.title	Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane	por
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.title	Tetrahedron Letters	por
person.familyName	Santos
person.givenName	Clementina M.M.
person.identifier.ciencia-id	9018-DB9C-C590
person.identifier.orcid	0000-0003-4380-7990
person.identifier.scopus-author-id	7201458663
rcaap.rights	openAccess	por
rcaap.type	article	por
relation.isAuthorOfPublication	64f662b6-775d-4ea0-bfd7-f527af0ac1a0
relation.isAuthorOfPublication.latestForDiscovery	64f662b6-775d-4ea0-bfd7-f527af0ac1a0