Publicação
Yerba mate aqueous extract improves the oxidative and inflammatory states of rats with adjuvant-induced arthritis
| dc.contributor.author | Correa, Vanesa G. | |
| dc.contributor.author | Sá-Nakanishi, Anacharis B. de | |
| dc.contributor.author | Gonçallves, Geferson de Almeida | |
| dc.contributor.author | Barros, Lillian | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.contributor.author | Bracht, Adelar | |
| dc.contributor.author | Peralta, Rosane M. | |
| dc.date.accessioned | 2018-02-19T10:00:00Z | |
| dc.date.accessioned | 2020-01-06T14:10:02Z | |
| dc.date.available | 2018-01-19T10:00:00Z | |
| dc.date.available | 2020-01-06T14:10:02Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Healthy and adjuvant-induced arthritic rats were treated for 23 days with daily doses of 400 and 800 mg kg−1 Ilex paraguariensis extract. This treatment (a) diminished the ROS levels in the liver and brain, (b) decreased oxidative protein and lipid damage in liver and brain, (c) increased the plasma antioxidant capacity, (d) increased the GSH levels and the GSH/GSSH ratio in both the liver and the brain, (e) almost restored the enzymatic activities linked to the metabolism of GSH–GSSG, and (f ) reversed the modified activities of xanthine oxidase, superoxide dismutase and catalase. The anti-inflammatory actions (firstly) and the antioxidant actions (in the second place) of the yerba mate constituents (e.g., chlorogenic acid derivatives) are the causes of these beneficial effects. Daily ingestion of traditional yerba mate beverages may be effective in attenuating the symptoms of inflammatory diseases, especially in older adults. | |
| dc.description.sponsorship | This work was financially supported by grants from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq-307944/2015-8), Coordenação do Aperfeiçoamento de Pessoal do Ensino Superior (CAPES) and Fundação Araucária. The authors are also indebted to Jailson Araújo Dantas for his technical assistance and to Dr Ciomar A. B. Amado for facilitating access to equipment of the Pharmacology and Therapeutics Department of the State University of Maringá. The authors are also grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013) and L. Barros contract. | |
| dc.description.version | info:eu-repo/semantics/publishedVersion | en_EN |
| dc.identifier.citation | Correa, Vanesa Gesser; De Sá-Nakanishi, Anacharis B.; GoncÄ…lves, Geferson De Almeida; Barros, Lillian; Ferreira, Isabel C.F.R.; Bracht, Adelar; Peralta, Rosane M. (2019). Yerba mate aqueous extract improves the oxidative and inflammatory states of rats with adjuvant-induced arthritis. Food and Function. ISSN 2042-6496. 10, p. 5682-5696 | en_EN |
| dc.identifier.doi | 10.1039/c9fo00491b | en_EN |
| dc.identifier.issn | 2042-6496 | |
| dc.identifier.uri | http://hdl.handle.net/10198/20258 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | en_EN |
| dc.title | Yerba mate aqueous extract improves the oxidative and inflammatory states of rats with adjuvant-induced arthritis | en_EN |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardNumber | UID/AGR/00690/2013 | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT | |
| oaire.fundingStream | 5876 | |
| person.familyName | Barros | |
| person.familyName | Ferreira | |
| person.givenName | Lillian | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 469085 | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 9616-35CB-D001 | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0002-9050-5189 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | J-3600-2013 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 35236343600 | |
| person.identifier.scopus-author-id | 36868826600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | en_EN |
| rcaap.type | article | en_EN |
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