Repository logo
 
Publication

Genetic information influence on phenolic composition and bioactivities of Ceratonia siliqua L. seeds

2022Conference object Open access
Simple item page
dc.contributor.authorMarcelino, Sandra Andreia
dc.contributor.authorMandim, Filipa
dc.contributor.authorOludemi, Taofiq
dc.contributor.authorDias, Maria Inês
dc.contributor.authorBarracosa, Paulo
dc.contributor.authorPrieto Lage, Miguel A.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2023-03-21T15:07:29Z
dc.date.available2023-03-21T15:07:29Z
dc.date.issued2022
dc.description.abstractCeratonia siliqua L., commonly known as the carob tree is native to the Mediterranean countries and is widely known and consumed. Due to its chemical constituents, flavoring properties, and nutritional benefits, it has the potential to be of significant importance to the food industry1. The carob bean is made up of 90% pulp and 10% seeds. Those seeds are widely used in the food industry as a thickening agent (E-410). However, knowledge about phenolic composition and its relation to biological properties is scarce. This study used seeds of thirteen carob varieties harvested in Algarve, Portugal. The phenolic composition of the hydroethanolic extracts was analyzed by HPLC-DAD-ESI/MS. The antioxidant, anti-inflammatory, cytotoxic and antibacterial properties of the extracts were also analysed. The phenolic composition was analyzed by HPLC-DAD-ESI/MS. Cytotoxic activity was evaluated by the colourimetric method of sulforhodamine B. Anti-inflammatory activity was determined by inhibition of NO production in murine macrophages. The antibacterial activity was evaluated through the method of successive microdilutions and the antioxidant activity through the TBARS and CAA assays. Seventeen phenolics compounds were tentatively identified, being (Epi)catechin dimer type  dimer and apigenin-O-hexosyl-pentoside the most abundant ones (3.08 – 11.67 mg/mL). All the varieties studied exhibited the capacity to inhibit TBARS formation. The extract obtained from the Gasparinha variety was the only one that inhibited the reactive oxygen species formation in the CAA assay. For the cytotoxic activity only Cavi, Cardeira and Pé Comprido varieties demonstrated the ability to inhibit the proliferation of the tumor cell lines tested, without showing a hepatotoxic effect. All extracts presented a broad-spectrum microbial growth inhibition without an efficient bactericidal power. These findings highlight Carob seed as a rich source of structurally diverse biomolecules with potential application as additives in food formulation development. However, further studies are needed to understand the correlation between phenolic compounds and the bioactive properties associated with carob seed tissues.pt_PT
dc.description.sponsorshipTo the Foundation for Science and Technology (FCT, Portugal) for financial support to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2021); PhD grant of Filipa Mandim (SFRH/146614/2019) and L. Barros contract. Also to FEDER for financial support through the project OliveBIOextract (NORTE-01-0247-FEDER-049865). This work is also supported by MICINN supporting the Ramón y Cajal grant for M.A. Prieto (RYC-2017-22891) and Juan de la Cierva Formation contract for T. Oludemi (FJC2019-042549-I).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMarcelino, Sandra Andreia; Mandim, Filipa; Oludemi, Taofiq; Dias, Maria Inês; Barracosa, Paulo; Prieto Lage, Miguel A.; Barros, Lillian (2022). Genetic information influence on phenolic composition and bioactivities of Ceratonia siliqua L. seeds. In Livro de Resumos do 12º Encontro Nacional de Cromatografia & XIV WARPA. Aveiropt_PT
dc.identifier.urihttp://hdl.handle.net/10198/27909
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Químicapt_PT
dc.relationLA/P/0007/2021pt_PT
dc.relationMountain Research Center
dc.relationMountain Research Center
dc.relationRYC-2017-22891pt_PT
dc.relationIntegrated strategies for the development of a novel functional beverage with sustainable production systems
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCeratonia siliqua L. seedspt_PT
dc.subjectResearch Subject Categories::TECHNOLOGY::Chemical engineering::Food technologypt_PT
dc.titleGenetic information influence on phenolic composition and bioactivities of Ceratonia siliqua L. seedspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleMountain Research Center
oaire.awardTitleIntegrated strategies for the development of a novel functional beverage with sustainable production systems
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F146614%2F2019/PT
oaire.citation.conferencePlaceAveiropt_PT
oaire.citation.endPage176pt_PT
oaire.citation.startPage176pt_PT
oaire.citation.titleLivro de Resumos do 12º Encontro Nacional de Cromatografia & XIV WARPApt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMarcelino
person.familyNameMandim
person.familyNameOludemi
person.familyNameDias
person.familyNamePrieto Lage
person.familyNameBarros
person.givenNameSandra Andreia
person.givenNameFilipa
person.givenNameTaofiq
person.givenNameMaria Inês
person.givenNameMiguel A.
person.givenNameLillian
person.identifier107688
person.identifier469085
person.identifier.ciencia-idF318-9049-EB99
person.identifier.ciencia-idE318-A5CD-6626
person.identifier.ciencia-id2A13-4BE6-C7CF
person.identifier.ciencia-id221E-1E00-AB74
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0003-1490-9445
person.identifier.orcid0000-0002-6494-2326
person.identifier.orcid0000-0003-2822-3532
person.identifier.orcid0000-0001-8744-7814
person.identifier.orcid0000-0002-3513-0054
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridM-8242-2013
person.identifier.ridG-4516-2011
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54388787000
person.identifier.scopus-author-id35937495700
person.identifier.scopus-author-id35236343600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationd116a005-efaf-410f-8dae-8ded6c79b9d9
relation.isAuthorOfPublicationbcc274d4-7e6c-46a8-8e49-2752f9dbfbcd
relation.isAuthorOfPublication74ac0f55-9896-40ec-8444-523044e80c4a
relation.isAuthorOfPublication7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isAuthorOfPublication13260615-fd28-4b8b-9dd4-8a8466007579
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isProjectOfPublication29718e93-4989-42bb-bcbc-4daff3870b25
relation.isProjectOfPublication0aac8939-28c2-46f4-ab6b-439dba7f9942
relation.isProjectOfPublication6f42bb4f-993a-4998-afc5-030cd08f965b
relation.isProjectOfPublication.latestForDiscovery6f42bb4f-993a-4998-afc5-030cd08f965b

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
11.pdf
Size:
670.04 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus