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Release studies of thymol and p-cymene from polylactide microcapsules

2012Journal article Restricted access
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dc.contributor.authorMartins, Isabel M.
dc.contributor.authorRodrigues, Sofia Nogueira
dc.contributor.authorBarreiro, M.F.
dc.contributor.authorRodrigues, Alírio
dc.date.accessioned2012-12-03T12:00:20Z
dc.date.available2012-12-03T12:00:20Z
dc.date.issued2012
dc.description.abstractThe objective of this work is to access the release behavior of thymol and p-cymene used as model core materials with PLA microcapsules. The microcapsules were obtained by a coacervation process developed in a previous work and present a spherical shape with mean particle size of 25 and 37 mu m for thymol and p-cymene, respectively. The results have shown that the release of thymol and p-cymene is faster in the first hour keeping almost constant in the subsequent days. The diffusion coefficient in the first hour of release was 1.99 X 10(-16) m(2)/s for thymol and 4.34 X 10(-16) m(2)/s for p-cymene. However, the diffusion was slower if considering a period of 5 days being the diffusion coefficients of 3.34 X 10(-19) m(2)/s for thymol and 3.45 X 10(-18) m(2)/s for cymene.por
dc.description.sponsorshipLSRE financing by FEDER/POCI/2010. Ph.D. schorlarship by Fundação para a Ciência e a Tecnologia (FCT) (SFRH/BD/43215/2008)por
dc.identifier.citationMartins, I.M.; Rodrigues, S.N.; Barreiro, M.F.; Rodrigues, A.E. (2012). Release studies of thymol and p-cymene from polylactide microcapsules. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH. 51:35, p.11565-11571por
dc.identifier.doi10.1021/ie301406f
dc.identifier.urihttp://hdl.handle.net/10198/7741
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherACSpor
dc.subjectEssential oilspor
dc.subjectMicrospherespor
dc.subjectPharmacokineticspor
dc.subjectPolymerspor
dc.titleRelease studies of thymol and p-cymene from polylactide microcapsulespor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage11571por
oaire.citation.issue35por
oaire.citation.startPage11565por
oaire.citation.titleINDUSTRIAL & ENGINEERING CHEMISTRY RESEARCHpor
oaire.citation.volume51por
person.familyNameBarreiro
person.givenNameFilomena
person.identifier.ciencia-id3418-47D5-5746
person.identifier.orcid0000-0002-6844-333X
person.identifier.ridL-9802-2014
person.identifier.scopus-author-id57188719717
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication0391987c-ba90-488b-839a-153447ce1f0f
relation.isAuthorOfPublication.latestForDiscovery0391987c-ba90-488b-839a-153447ce1f0f

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