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Occurrence of polycyclic aromatic hydrocarbon metabolites in urine of portuguese firefighters

dc.contributor.authorOliveira, Marta
dc.contributor.authorSlezakova, Klara
dc.contributor.authorFernandes, Adília
dc.contributor.authorVaz, Josiana A.
dc.contributor.authorDelerue-Matos, Cristina
dc.contributor.authorTeixeira, João Paulo Fernandes
dc.contributor.authorPereira, Maria do Carmo
dc.contributor.authorMorais, Simone
dc.date.accessioned2016-11-21T17:23:38Z
dc.date.available2016-11-21T17:23:38Z
dc.date.issued2015
dc.description.abstractThe present work estimates occupational exposure of healthy and non-smoking Portuguese firefighters to polycyclic aromatic hydrocarbons (PAHs) through the analysis of four urinary metabolites (OH-PAHs): 1-hydroxyacenaphthene, 1-hydroxynaphthalene, 1-hydroxypyrene (PAH biomarker of exposure), and 3-hydroxybenzo[a]pyrene (PAH biomarker of carcinogenicity). Firemen from several Portuguese corporations were asked to provide urine samples during the winter period (without exposition to fires; pre-fire season) and during the summer season of 2014 after fires fighting. The selected OH-PAHs were extracted from urine samples by solid-phase extraction and analyzed by high-performance liquid chromatography with fluorescence detection. Normalization of the urinary PAH-metabolite levels was achieved by analyzing the creatinine concentrations. 1-hydroxynaphthalene and 1-hydroxyacenaphthene were the most abundant metabolites, followed by 1-hydroxypyrene. The metabolite 3- hydroxybenzo[a]pyrene was not detected. Total OH-PAHs ranged from 0.02 to 4.01 μmol/mol creatinine and between 0.55 to 8.39 μmol/mol creatinine, respectively, for non exposed and exposed firefighters. In general, the detected concentrations of urinary PAH metabolites were higher during the fire season than in the winter season.pt_PT
dc.identifier.citationOliveira, M.; Slezakova, K.; Fernandes, Adília; Vaz, Josiana A.; Delerue-Matos, C.; Teixeira, J.P.; Pereira, M.C.; Morais, S. (2015). Occurrence of polycyclic aromatic hydrocarbon metabolites in urine of portuguese firefighters. In14th International Conference on Environmental Science and Technology (cest 2015) Will Take Place 3-5.sep.2015 Rhodes, Greecept_PT
dc.identifier.urihttp://hdl.handle.net/10198/13521
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherT.D. Lekkaspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFirefighters,pt_PT
dc.subjectOccupational exposurept_PT
dc.subjectBiomonitoringpt_PT
dc.subjectUrinary pah-metabolitespt_PT
dc.subjectLiquid chromatographypt_PT
dc.titleOccurrence of polycyclic aromatic hydrocarbon metabolites in urine of portuguese firefighterspt_PT
dc.typeconference paper
dspace.entity.typePublication
oaire.citation.conferencePlaceRhodes, Greecept_PT
oaire.citation.title14th International Conference on Environmental Science and Technology (cest 2015) Will Take Placept_PT
person.familyNameFernandes
person.familyNameVaz
person.givenNameAdília
person.givenNameJosiana A.
person.identifier.ciencia-id0514-76CD-8CCF
person.identifier.ciencia-id171B-88BA-64F5
person.identifier.orcid0000-0003-1658-4509
person.identifier.orcid0000-0002-6989-1169
person.identifier.ridV-8399-2017
person.identifier.scopus-author-id56489572200
person.identifier.scopus-author-id16305323200
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationbdfceda8-18d6-4b63-b6f9-d3870cd0dbb0
relation.isAuthorOfPublication1c1a2cb9-5a36-47ba-bca0-ffcbef28df18
relation.isAuthorOfPublication.latestForDiscovery1c1a2cb9-5a36-47ba-bca0-ffcbef28df18

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