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Advisor(s)
Abstract(s)
Chalcones are a class of naturally occurring flavonoid compounds associated to a
variety of biological and pharmacological properties. Several reviews have been published
describing the synthesis and biological properties of a vast array of analogues. However, overviews
on the reactivity of chalcones has only been explored in a few accounts. To fill this gap, a
systematic survey on the most recent developments in the transition metal-catalyzed transformation
of chalcones was performed. The chemistry of copper, palladium, zinc, iron,
manganese, nickel, ruthenium, cobalt, rhodium, iridium, silver, indium, gold, titanium,
platinum, among others, as versatile catalysts will be highlighted, covering the literature from
year 2000 to 2023, in more than 380 publications.
Description
Keywords
Cycloaddition Conjugate addition Cross-coupling Hydrogenation Epoxidation
Pedagogical Context
Citation
Santos, Clementina M. M; Silva, Artur M. S. (2024). Transition Metal‐Catalyzed Transformations of Chalcones. The Chemical Record. ISSN 1527-8999. 24:8, p. 1-55
Publisher
Wiley